Stability of non-invasive human neurophysiological parameters using transcranial magnetic stimulatio

Recruiting

• Conditions: LTP / learning; 10009841

• Registration Number: NL-OMON40291
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 96

Inclusion Criteria

Subjects can be included if:
• They are in good health, based on medical history information, including current physical and mental condition
• They are medication free (females: except for hormonal contraceptives) and abstinent from the use of illicit drugs
• They are right-handed
• They are capable and willing to give written informed consent
• They are within the age range of 18-40 years

Exclusion Criteria

Subjects will be excluded if:
• They are women who are pregnant or lactating
• They have a history of psychiatric illness and/or psychotherapeutic treatments
• They have a history of neurological illnesses
• They fulfil any of the exclusion criteria concerning the safety of TMS as assessed by means of the Transcranial magnetic stimulation Adult Safety Screen (TASS)
• They cannot understand the Dutch language sufficiently to understand the purposes and implications of the experiment

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The difference in the amplitude of the MEP of the APB muscle between baseline<br /><br>TMS and after PAS, Theta-burst rTMS (TBS) or ppTMS as obtained during session 1<br /><br>and session 2.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The neuropsychological tests scores.</p><br>