Influence of extracorporeal circulation on perioperative cefuroxime concentrations in bypass surgery patients.Exploratory, prospective, open-label, monocentric study to investigate the influence of operative extracorporeal circulation on perioperative cefuroxime concentrations using microdialysis technique in bypass surgery patients

niversitätsklinikum Augsburg0 个研究点目标入组 30 人开始时间: 2023年6月27日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•Patients undergoing elective bypass surgery who require perioperative antibiotic prophylaxis
•- Written declaration of consent by the patient

•- Patients who have received therapy with cefuroxime in the 72 hours prior to surgery.
•- Known allergic reaction, hypersensitivity or contraindication to cefuroxime or other ß-lactam antibiotics (e.g. penicillins, cephalosporins).
•- Severe renal insufficiency < 20 ml/min/1.73 m2
•- Non-guideline discontinuation of blood thinning medications
•Medications if urgency does not allow the surgery to be postponed for the appropriate number of days.
•- Active participation in other interventional studies according to AMG or MPDG
•- Women during pregnancy or breastfeeding

发起方

niversitätsklinikum Augsburg