DRKS00030889
Recruiting
N/A
Influence of extracorporeal circulation on perioperative cefuroxime concentrations in bypass surgery patients.Exploratory, prospective, open-label, monocentric study to investigate the influence of operative extracorporeal circulation on perioperative cefuroxime concentrations using microdialysis technique in bypass surgery patients
niversitätsklinikum Augsburg0 sites30 target enrollmentJune 27, 2023
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- I25
- Sponsor
- niversitätsklinikum Augsburg
- Enrollment
- 30
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients undergoing elective bypass surgery who require perioperative antibiotic prophylaxis
- •\- Written declaration of consent by the patient
Exclusion Criteria
- •\- Patients who have received therapy with cefuroxime in the 72 hours prior to surgery.
- •\- Known allergic reaction, hypersensitivity or contraindication to cefuroxime or other ß\-lactam antibiotics (e.g. penicillins, cephalosporins).
- •\- Severe renal insufficiency \< 20 ml/min/1\.73 m2
- •\- Non\-guideline discontinuation of blood thinning medications
- •Medications if urgency does not allow the surgery to be postponed for the appropriate number of days.
- •\- Active participation in other interventional studies according to AMG or MPDG
- •\- Women during pregnancy or breastfeeding
Outcomes
Primary Outcomes
Not specified
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