Outcome of Transarterial Chemo-embolization (TACE) in Hepatocellular Carcinoma Patients With Partial Portal Vein Thrombosis
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 30
- 主要终点
- changes in Radiological Response in the (CT/ MRI) after the intervention
研究概览
简要总结
Portal vein tumor invasion (PVT) is a common complication in HCC. the studyb Aimed to assess the outcomes after TACE in patients with branch PVT regarding Child classification, radiological response and 1 year survival.
详细描述
Thirty HCC patients (24 male, 6 females) Child A cirrhotics with branch PVT. Follow up was done at 1, 3, 6 and 12 months after first TACE. All patients underwent laboratory investigations including liver function tests to assess deterioration in liver functions, triphasic spiral CT to assess radiological response according to mRECIST criteria. Survival analysis was performed using Kaplan-Meier estimations.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with newly diagnosed HCC,
- •Child class A and
- •Portal vein branch tumoral thrombus (proved by imaging)
- •written informed consent
排除标准
- •patients with Child class B and C,
- •main Portal vein thrombosis,
- •previous management for HCC,
- •Arterio-portal shunt
- •refused to be enrolled
结局指标
主要结局
changes in Radiological Response in the (CT/ MRI) after the intervention
时间窗: 1 year
次要结局
未报告次要终点
研究者
Iman Fawzy Montasser
Associate professor of tropical medicine , Ain Shams university
Ain Shams University