Outcome of Transarterial Chemo-embolization (TACE) in Hepatocellular Carcinoma Patients With Partial Portal Vein Thrombosis
Phase 4
Completed
- Conditions
- Hepatocellular Carcinoma (HCC)
- Registration Number
- NCT03007212
- Lead Sponsor
- Ain Shams University
- Brief Summary
Portal vein tumor invasion (PVT) is a common complication in HCC. the studyb Aimed to assess the outcomes after TACE in patients with branch PVT regarding Child classification, radiological response and 1 year survival.
- Detailed Description
Thirty HCC patients (24 male, 6 females) Child A cirrhotics with branch PVT. Follow up was done at 1, 3, 6 and 12 months after first TACE. All patients underwent laboratory investigations including liver function tests to assess deterioration in liver functions, triphasic spiral CT to assess radiological response according to mRECIST criteria. Survival analysis was performed using Kaplan-Meier estimations.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
- Patients with newly diagnosed HCC,
- Child class A and
- Portal vein branch tumoral thrombus (proved by imaging)
- written informed consent
Exclusion Criteria
- patients with Child class B and C,
- main Portal vein thrombosis,
- previous management for HCC,
- Arterio-portal shunt
- refused to be enrolled
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method changes in Radiological Response in the (CT/ MRI) after the intervention 1 year
- Secondary Outcome Measures
Name Time Method