A clinical study to compare effect of Darvighrita and Yashtimadhughrita for local application in parikartika (fissure in ano)

Not yet recruiting

• Conditions: Acute anal fissure,

• Registration Number: CTRI/2020/03/023909
• Lead Sponsor: PDEAs college of ayurved and research centre

Brief Summary

Parikartika is one of the commonest anorectal diseases. This disease is not life threatening but very painful for the sufferers in this modern era where the medical science is on peak requires surgical intervention for Fissure-in-Ano. These conventional surgical procedures such as Lord’s dilatation, Fissurectomy, Sphincterotomy14 etc. The result of all these procedures causes many complications18,24.

                                                                                           To bring back, the past glory of Ayurvedi chikitsa, in the field of proctology has lot of scope for research25. Hence, this condition has been attracting Ayurvedic surgeons and physicians for ideal and suitable curative medication .Sushruta had mentioned 4 fold therapeutic procedures such as Oushadi, Kshara, Agni and Shastra karma4. Thus, in the present study the drug “DarviGhrita†selected as Oushadi and applied in the form of Picchu. Thus, in this study, the attempt is being made to observe the effect of “DarviGhrita†in treatment of Parikartika.

 So far, there have been many researches carried out in different institutions regarding Parikartika19,21,22. Moreover, there has been no work carried out on local management of Parikartika with “DarviGhritaâ€. Hence, an attempt is being made to see the effect of “DarviGhrita†instead of any surgical intervention

Detailed Description

Not available

Study Timeline

• Study Start: 2020-03-20
• Last Update Posted: 2020-06-21

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 68

Inclusion Criteria

• A.Patients diagnosed as having Parikartika(Fissure-in-Ano) B.
• Patients of both sexes in between the age group of 18 and 60years C.Patients of Parikartika with systemic diseases like Diabetes and Hypertension which are well under control were also included in the study.D.Female patients with pregnancy will be also included.

Exclusion Criteria

• Patients having Parikartika (Fissure-in-Ano) secondary to Ulcerative colitis, Chron’s disease, Syphilis, Tuberculosis and Ca. of rectum of anal canal.
• Chronic fissure.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the efficacy of DARVI GHRITA and YASHTIMADHU GHRITA in Parikartika within 14 days	5th,7th,10th,14th days

Secondary Outcome Measures

Name	Time	Method
To observe adverse drug reaction, if any.	5th,7th,10th,14th day

Trial Locations

Locations (1)

Ayurved rugnalay and sterling multispeciality hospital,Nigdi; 🇮🇳 Pune, MAHARASHTRA, India

Ayurved rugnalay and sterling multispeciality hospital,Nigdi

🇮🇳Pune, MAHARASHTRA, India

Atul Baburao Tambade

Principal investigator

8600378637

atatultambade@gmail.com