Screening Latent Tuberculosis Infection and Observing Preventive Therapy in Kidney Transplantation
Not Applicable
- Conditions
- Kidney Transplantation
- Interventions
- Other: Examination of latent tuberculosis
- Registration Number
- NCT02782416
- Lead Sponsor
- National Taiwan University Hospital
- Brief Summary
Study the prevalence of LTBI in patients who are waiting renal transplant and monitor the incidence of active TB
- Detailed Description
Study the prevalence of LTBI in patients who are waiting renal transplant and monitor the incidence of active TB
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 800
Inclusion Criteria
- Age between 20-65 and match one of below
- Waiting renal transplant or status post renal transplant
- Receiving long term dialysis
Exclusion Criteria
- Not agree to be enrolled
- Suspected active TB
- HIV patients
- Viral hepatitis
- Using immunosuppressants within 3 months before enrollment
- Receiving lymphokine therapy
- Hemoglobin < 8 g/dL
- Serum bilirubin > 2.5 mg/dL
- AST or ALT > 2 times of upper normal limit
- Lactation or pregnancy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Status post renal transplant Examination of latent tuberculosis patients who have received renal transplant Not waiting for renal transplant Examination of latent tuberculosis Dialysis patients who are not waiting for renal transplant Waiting for renal transplant_ screening of LTBI Examination of latent tuberculosis patients with renal failure and are waiting for renal transplant We do routine examination in addition to LTBI check
- Primary Outcome Measures
Name Time Method percentage of active TB 4 years
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
National Taiwan University Hospital
🇨🇳Taipei, Taiwan