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Nutritional Therapy on Underweight Critically Ill Patients: an Observational Study

Conditions
Underweight
Critical Illness
Registration Number
NCT03398343
Lead Sponsor
Hospital de Clinicas de Porto Alegre
Brief Summary

Critically ill patients with body mass index (BMI) inferior to 20 kg/m2 have worse outcomes compared to normal and overweight patients. The impact nutrition therapy in this population is not yet stablished. There is a concern that too low caloric intake might worse their malnutrition; on the other hand, overfeeding is always a risk with serious consequences.

The hypothesis of this study is that nutritional support, especially caloric and protein intake, can influence the outcome of underweight critically ill patients.

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
450
Inclusion Criteria
  • Ages eligible for study: 18 years and older
  • Gender eligible: both
  • Nutrition therapy: enteral, parenteral feeding, nothing by mouth
Exclusion Criteria
  • Palliative care
  • Exclusively oral nutrition
  • Pregnancy
  • Life expectancy inferior 24 hours
  • ICU readmission

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Mortalitythrough study completion (up to a year)

All patients will be followed until live hospital discharge or death

Secondary Outcome Measures
NameTimeMethod
ICU length of staythrough study completion (up to a year)

patients will be followed until ICU discharge or death

Need and duration of mechanical ventilationthrough study completion (up to a year)

all patients for which mechanical ventilation is necessary will be followed until it is no longer necessary

Trial Locations

Locations (1)

HCPA, Hospital de Clinicas de Porto Alegre

🇧🇷

Porto Alegre, Rio Grande Do Sul, Brazil

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