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Clinical Trials/NCT04891562
NCT04891562
Completed
Not Applicable

Rhythmic Interlimb Coordination in Children with Developmental Coordination Disorder Compared to Typical Developing Children: the Effect of Individual, Task and Environmental Constraints

Hasselt University1 site in 1 country52 target enrollmentJanuary 25, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Developmental Coordination Disorder
Sponsor
Hasselt University
Enrollment
52
Locations
1
Primary Endpoint
Auditory motor coupling - Relative phase angle
Status
Completed
Last Updated
last year

Overview

Brief Summary

This study is a case-controlled observational study, involving children with Developmental Coordination Disorder (DCD) and typically developing children with an age from 8 up to 12 years old. The study aims to investigate interlimb coordination of the lower limbs and sensorimotor synchronization ability in children with DCD compared to age-matched typically developing children during gait and fundamental lower limb coordination task to 2 metronomes with different temporal structures. The study consists of a maximum of 4 sessions (2 descriptive sessions, 2 experimental sessions), each lasting around 60 minutes. Depending on the preferences of the child and parents, the sessions can be combined in 2 sessions of 2 hours. During the first descriptive session, the participant will perform the m-ABC2 test to assess gross and fine motor function. The MBEMA-s will be used to examine rhythm perception ability. During the second descriptive session, children will perform the Kids BESTest to examine postural control, and two cognitive tests (digit span, go-no/go test) to assess executive functioning. During the third visit (experimental session), interlimb coordination and synchronization will be investigated during three tasks with different dynamic balance demands (seated, walking and running) in three conditions: in silence, to beats in isochronous metronome (discrete structure), to beats in non-isochronous metronomes (sinusoidal structure). In the last experimental session, the tempi of the auditory metronomes will be set at higher and lower tempi than the preferred comfortable tempo of the child.

Registry
clinicaltrials.gov
Start Date
January 25, 2021
End Date
January 18, 2023
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Hasselt University
Responsible Party
Principal Investigator
Principal Investigator

Eugene Rameckers

Principal Investigator

Hasselt University

Eligibility Criteria

Inclusion Criteria

  • are aged between 8-12 years
  • have no medical conditions that could impede their motor abilities.
  • Children with a diagnosis of DCD, consistent with the DSM-V (Blank et al., 2019), or total percentile score \<P16 on the movement assessment battery for children edition 2 (m-ABC-2), will be included in the group of (probably) DCD.
  • The m-ABC score total of typical developing children needs to be ≥P25 for inclusion

Exclusion Criteria

  • have other neurological, orthopaedical, cardiorespiratory or intellectual impairment that could affect their motor abilities (verified using a health questionnaire)

Outcomes

Primary Outcomes

Auditory motor coupling - Relative phase angle

Time Frame: week 3

Synchronization accuracy of steps to the beats during walking and running; and of the knee flexion-extension movement to the beats during the seated task. Relative phase angle, asynchrony in time to quantify synchronization accuracy (in degrees and in milliseconds respectively)

Phase coordination index (PCI)

Time Frame: week 3

PCI is a measurement of consistency and accuracy in generating a series of anti-phase left - right stepping phases. Detailed information is described in Plotnik et al. (2007). Shortly, phase represent the relative timing of contralateral heel strikes, determining the phase, and normalize the step time with respect to the stride time (Plotnik, Giladi, \& Hausdorff, 2007). Ideal interlimb coordination for each step is 180°. The consistency of the phase generation is represented by the Coefficient of variation of the series of the relative timing of the stepping of one leg with respect to the gait cycle.A lower PCI%, closer to zero, indicates a better antiphase interlimb coordination pattern.

Auditory motor coupling - Resultant Vector Length to quantify synchronization consistency

Time Frame: week 3

Synchronization consistency of steps to the beats during walking and running; and of the knee flexion-extension movement to the beats during the seated task Resultant Vector Length to quantify synchronization consistency. If the distribution of the relative phase angles over time is consistent, it results in a high resultant vector length (maximum value 1). If the synchronization is not consistent, the resultant vector length will be low (minimum value 0)

Secondary Outcomes

  • step width (cm)(week 3)
  • velocity (m/s)(week 3)
  • stride length (cm)(week 3)
  • movement frequency(week 3)
  • cadence (step/minute)(week 3)
  • double support (%gait cycle)(week 3)
  • movement amplitude(week 3)
  • The m-ABC (second edition)(Baseline)
  • Montreal Battery of Evaluation of Musical Abilities (MBEMA-s)(Baseline)
  • Kids BESTest(week 1)
  • digit span(week 1)
  • go-no/go test(week 1)

Study Sites (1)

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