Role of new parameter by renal doppler study to predict onset of acute kidney injury in patients who have developed sepsis.

Not yet recruiting

• Conditions: Other acute kidney failure,

• Registration Number: CTRI/2021/09/036391
• Lead Sponsor: AIIMS New Delhi

Brief Summary

Sepsis is a leading cause of Acute kidney injury. Urine output and serum creatinine are not very accurate in predicting onset of AKI in sepsis. Available biomarkers have problems like availability, cost, sensitivity. Ultrasonography has come up as an excellent bedside technique in a variety of fields in ICU care. Renal resistive index has already shown to predict onset of AKI in post surgical patients. Trials on sepsis has not been done. We are wanting to see the role of renal arterio venous coupling, a new usg based marker, in the prediction of acute kidney injury in patients with sepsis.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2021-08-09
• Study Start: 2021-09-15

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• 1All 18-65 years old patients admitted in AIIMS with sepsis during study duration who will give consent for the study 2Feasibility of Renal doppler examinations within first 12 hours of admission.
• 3Sepsis defined as by Sepsis 3 criteria.

Exclusion Criteria

1Poor abdominal echogenicity 2Chronic kidney disease 3AKI on admission 4Unilateral nephrectomy 5Renal transplant patients 6Unilateral or bilateral hydronephrosis 7Pregnant 8Renal tumor 9Suspected intra abdominal hypertension.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Primary objective	Primary objective | The goals of this study are to determine the relationship between the renal doppler parameters calculated during first 12 hours of ICU admission and MAKE-30 (Major Adverse Kidney Events within 30 days) in septic patients admitted to the general ICU.
The goals of this study are to determine the relationship between the renal doppler parameters calculated during first 12 hours of ICU admission and MAKE-30 (Major Adverse Kidney Events within 30 days) in septic patients admitted to the general ICU.	Primary objective | The goals of this study are to determine the relationship between the renal doppler parameters calculated during first 12 hours of ICU admission and MAKE-30 (Major Adverse Kidney Events within 30 days) in septic patients admitted to the general ICU.

Secondary Outcome Measures

Name	Time	Method
Secondary objectives	To identify if these parameters can predict

Trial Locations

Locations (1)

All India Institute Of Medical Sciences New Delhi; 🇮🇳 South, DELHI, India

All India Institute Of Medical Sciences New Delhi

🇮🇳South, DELHI, India

Sangshaptak Saha

Principal investigator

09836139666

goodced@gmail.com