Corneal transplantation by ultra-thin DSAEK: thinner grafts, better vision?
Completed
- Conditions
- Irreversible corneal endothelial failure.
- Registration Number
- NL-OMON25888
- Lead Sponsor
- Maastricht University Medical Center / University Eye Clinic Maastricht
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 66
Inclusion Criteria
Patients eligible for DSAEK or ultra-thin DSAEK are patients with:
1. Endothelial dysfunction caused by Fuchs’ endothelial dystrophy;
Exclusion Criteria
1. Previous corneal transplantation;
2. Human leukocyte antigen typed keratoplasty;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary outcome measure is best corrected visual acuity (BCVA) 12 months postoperatively.
- Secondary Outcome Measures
Name Time Method Secondary outcome measures are contrast acuity, refractive and topographic astigmatism, quality of vision (measured by contrast sensitivity measurements and stray light measurements), endothelial cell loss, incidence of graft rejection, primary graft failure, cornea donor loss due to preparation, and generic and vision-related quality of life (measured by validated questionnaires). Furthermore, adverse events, including complications, will be reported for each patient.