Corneal Transplantation by DMEK - is it really better than DSAEK?

Completed

• Conditions: 10015957; Fuchs' dystrophy; Fuchs' Corneal Endothelial Dystrophy (FECD); 10047518

• Registration Number: NL-OMON43481
• Lead Sponsor: Medisch Universitair Ziekenhuis Maastricht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 50

Inclusion Criteria

- Irreversible cornea decompensation caused by Fuchs Corneal Endothelial Dystrophy
- A minimum patient age of 21

Exclusion Criteria

- Ocular comorbities other than cataract
- Previous corneal transplantation
- Human leukocyte antigen (HLA) matched keratoplasty
- Inability to complete follow-up

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary outcome measure is best-corrected visual acuity. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary outcome measures are contrast acuity, astigmatism, quality of vision,<br /><br>endothelial cell loss, incidence of graft rejection, primary graft failure,<br /><br>cornea donor loss due to preparation, and generic and vision-related quality of<br /><br>life.</p><br>