Evaluation of the cardiovascular effects of Medicinal Cannabis

Recruiting

• Conditions: Healthy Volunteers; D26.528

• Registration Number: RBR-9grvg8d
• Lead Sponsor: Hospital de Clínicas da Universidade Federal do Paraná

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-08-15
• Last Update Posted: 19 August 2024
• Study Completion: 2026-12-01

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

adults of both sexes; older than 18 years old; be a patient at cannabis clinics medicine or the Basic Unit of Health; for the treatment group, carry out medical cannabis treatment on a continuous basis

Exclusion Criteria

patients with heart failure; patients with valvular heart disease; patients with infectious endocarditis; patients with peripheral arterial disease serious; patients on hemodialysis with fistula arteriovenous; patients with cardiac arrhythmias; patients with coronary disease ischemic (history of Acute Myocardial Infarction AMI) Systemic sclerosis; any decompensated chronic disease;history of syncope and collapse; pregnant women

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Assessment of Heart Rate Variability characteristics between treatment groups and control groups, according to time-domain and non-linear results analysis parameters;Assessment of the minimum, maximum and average values ??of the Peripheral Perfusion Index between treatment groups and control groups, according to the analysis of its variation over time;Assessment of the minimum, maximum and average Heart Rate values ??between treatment groups and control groups, according to the analysis of its variation over time;Assessment of the minimum, maximum and average Blood Pressure values ??between treatment groups and control groups, according to the analysis of its variation over time;Assessment of the minimum, maximum and average values ??of Oxygen Saturation between treatment groups and control groups, according to the analysis of its variation over time

Secondary Outcome Measures

Name	Time	Method
Possible correlations between Heart Rate Variability and demographic data;Possible correlations between Peripheral Perfusion Index and demographic data;Possible correlations between Heart Rate and demographic data;Possible correlations between Blood Pressure and demographic data;Possible correlations between Oxygen Saturation and demographic data