Post-delirium Cognitive Impairment * PET and Neuropsychological Characteristics

Completed

• Conditions: Delirium; dementie; 10007951; 10012221

• Registration Number: NL-OMON36224
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Trial ended prematurely

Detailed Description

Not available

Study Timeline

• Study Completion: 2013-05-13
• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 1

Inclusion Criteria

Cases/controls: 1) age >65 jaar
Cases: 2) Clinical diagnosis of delirium during hospital admission, 3) Development of sepsis <14 days prior to delirium, 4) Clinical recovery from delirium at discharge.

Exclusion Criteria

1) Diagnosis of dementia or other major central nervous system pathology or psychiatric disease; 2) Previous episode of delirium; 3) Indication of prior cognitive impairment; 4) History of alcohol/substance abuse or severe headtrauma.
Cases: 5) Physical disability at discharge necessitating discharge to a nursing facility

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>1) Cerebral PK11195 binding potential (BP).<br /><br>2) Test-score on different neuropsychological domains.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>1) Duration of delirium.<br /><br>2) DRS-R-98.<br /><br>3) MMSE.</p><br>