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Risk Factors for Postoperative Pancreatic Fistula Following Non-traumatic Pancreatic Surgery. Retrospective Observational Study.

Completed
Conditions
Pancreas Neoplasm
Registration Number
NCT05711433
Lead Sponsor
Zagazig University
Brief Summary

Postoperative pancreatic fistula is a potentially fatal sequela with substantial morbidity and mortality. A retrospective observational study was conducted in the surgical unit of Zagazig university hospital . Three hundred forty-seven patients were admitted with a clinical diagnosis of pancreatic fistula following both open and laparoscopic approaches for pancreatic benign and malignant tumors.

Detailed Description

Postoperative pancreatic fistula is a potentially fatal sequela with substantial morbidity and mortality. POPF incidence and risk factors vary.

A retrospective observational study was conducted in the surgical unit of Zagazig university hospital . Three hundred forty-seven patients were admitted with a clinical diagnosis of pancreatic fistula following both open and laparoscopic approaches for pancreatic benign and malignant tumors.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
347
Inclusion Criteria
  • > 18 years,
  • both sexes,
  • respectablee pancreaticoduodenal tumors, or chronic pancreatitis
Exclusion Criteria
  • <18 years,
  • Patients who underwent total pancreatectomies,
  • Patients discovered intraoperatively to be fixed to portal vein or superior mesenteric artery, traumatic pancreatic surgeries, postoperative associated gastric or biliary leak, pancreaticoduodenal cancers infiltrating the colon, stomach or liver.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
incidence of postoperative pancreatic fistula3.5 years

an amylase level in the fluid collected from the drain on the third postoperative day (POD) that was \> three times the serum amylase level

Secondary Outcome Measures
NameTimeMethod
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