Impact of Lower Limb Spasticity on Tibial Nerve Entrapment in Patients With Stroke

October 6 University1 site in 1 country100 target enrollmentMarch 20, 2023

ConditionsNeuropathy Stroke

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Neuropathy
Sponsor: October 6 University
Enrollment: 100
Locations: 1
Primary Endpoint: Electrodiagnostic testing
Status: Active, not recruiting
Last Updated: 2 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Stroke is the most common cause of mortality and is one of the most common causes of morbidity in the world. Polyneuropathies and entrapment neuropathies are known as the complications of stroke

Registry

clinicaltrials.gov

Start Date

March 20, 2023

End Date

October 20, 2023

Last Updated

2 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

October 6 University

Responsible Party

Principal Investigator

Hosam Magdy Metwally

Lecturer of physical therapy for neurology

October 6 University

Eligibility Criteria

Inclusion Criteria

•1- A hundred patients with hemiplegia /paresis subsequent to a stroke as diagnosed by CT or MRI.
•2- A hundred patients from both sexes, their ages ranged from (55-65) years. 3- Body weight of patients was ranged from(55 -95 kg) ,while their height was from (151-185 cm) and BMI was ranged from (20-30 kg/m2).
•4- Duration of illness (6 - 9 months post stroke). 5- Patients have spasticity ranging from grade 1 to grade 3 according to modified Ashworth scale 6- Patients were medically stable

Exclusion Criteria

•1- Patients with lumbosacral sciatica that could mimic TTS or interfere with its evaluation 2- Patients with tibial neuropathy, significant polyneuropathy, or marked orthopedic abnormalities; 3- Patients with contractures 4- Patients with psychological disturbance or seizures 5- Systemic diseases known to cause TTS, such as diabetes mellitus, hypothyroidism, rheumatoid arthritis, or chronic renal failure;

Outcomes

Primary Outcomes

Electrodiagnostic testing

Time Frame: 30 minutes

Electrodiagnostic testing (electromyography and nerve conduction velocity) can objectively verify the tibial nerve dysfunction. Electrodiagnosis rests upon demonstrating impaired tibial nerve conduction across the tarsal tunnel in context of normal conduction. Compression results in damage to the myelin sheath and manifests as delayed latencies and slowed conduction velocities