Does a weaning protocol facilitate liberation from mechanical ventilation in tracheostomized brain-injured patients?

Not Applicable

• Conditions: weaning failure; Respiratory - Other respiratory disorders / diseases; Neurological - Other neurological disorders

• Registration Number: ACTRN12612000372886
• Lead Sponsor: niversita del Piemonte Orientale Amedeo Avogadro”, Alessandria-Novara-Vercelli

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-04-02
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Stopped early
• Sex: All
• Target Recruitment: 280

Inclusion Criteria

Patients wii be included if:
1) admitted for neurologic disorders;
2) age > 18 years,
3) mechanical ventilation >12 hours,
4) no need for continuous sedative infusion and/or controlled mechanical ventilation;
5) ability to trigger the ventilator;
6) presence of tracheotomy.

Exclusion Criteria

1) preexisting decision to limit life support.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reduction (%) of weaning failure.<br>The weaning failure will be defined as number of patients who are reconnected to the ventilator in the following 48 hours after the disconnection over the total number of patients. As we expect a reduction of weaning failure in the Intervention group, the difference between the percentage of weaning failure between the Control and Intervention groups will be the Reduction (%) of weaning failure.<br>These data, can be assessed by looking at the medical records database available in our hospital.[First 48 hours after disconnection from ventilator]