Genicular artery embolisation and the effect on Knee Osteoarthritis - a randomised controlled trial.

Not Applicable

• Conditions: Knee osteoarthritis; Musculoskeletal - Osteoarthritis

• Registration Number: ACTRN12622001157763
• Lead Sponsor: South Western Sydney Local health District

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-08-24
• Last Update Posted: 29 August 2022

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 54

Inclusion Criteria

>40 years of age.
Grade 2 and 3 knee Osteoarthritis on plain radiographs (Kellgren-lawrence scale).
Knee pain for 6 months or more, moderate to severe knee pain (VAS >50mm).
Pain refractory to conservative management for at least 3 months.
Patients capable of consenting for the trial.

Exclusion Criteria

Current local infection.
Life expectancy is less than 6 months.
Active malignancy.
Grade 1 or 4 knee OA on x-rays as per Kellgren-Lawrence Grading scale.
Known advanced atherosclerosis in lower limb.
Rheumatoid or infectious arthritis.
Prior ipsilateral knee surgery excluding arthroscopic surgery more than three months ago.
Uncorrectable coagulopathy greater with INR greater than 1.5 (APTT will not be taken).
Renal dysfunction as defined by eGFR <45 within the last 60 days.
Contraindications for MR imaging.
Known history of allergy to contrast media.
Women who are lactating, pregnant or trying to become pregnant.
Patients with a history of psychological illness, especially severe depression.

Study & Design

• Study Type: Interventional
• Study Design: Not specified