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Randomized Study of Intensive One-on-one Behavioral Treatment for Preschool Aged Children With Autism

Not Applicable
Completed
Conditions
Autistic Disorder
Registration Number
NCT00004449
Lead Sponsor
University of California, Los Angeles
Brief Summary

OBJECTIVES: I. Determine the effectiveness of intensive one-on-one behavioral treatment in the home or neighborhood compared with at home, individualized, parent training in preschool aged children with autism.

II. Identify intake measures that predict differences in outcome between subjects in the experimental group.

Detailed Description

PROTOCOL OUTLINE: This is a randomized study. Children are randomized to receive either 35 hours of intensive one-on-one behavioral treatment in the home and neighborhood for 2 years or individualized, in home parent training for 6 months.

A common group of tests to evaluate autism are administered at intake, 12 and 24 months into treatment, and when patients reach age 6.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
102
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Primary Outcome Measures
NameTimeMethod
Wechsler Preschool and Primary Scales of Intelligence, 3rd ed.yearly for up to 4 years

IQ

Bayley Scales of Infant Developmentyearly for up to 4 years

Alternate cognitive test administered to participants who did not achieve basal on WPPSI-III

Secondary Outcome Measures
NameTimeMethod
Merrill-Palmer Scale of Mental Testsyearly for up to 4 years

Nonverbal cognitive skills

Vineland Adaptive Behavior Scales - Survey Editionyearly for up to 4 years

Parent interview on child's adaptive functioning

Reynell Developmental Language Scalesyearly for up to 4 years

Language comprehension and expressive language

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