Study of Paclitaxel and Carboplatin chemotherapy in metastatic breast carcinoma
- Conditions
- Health Condition 1: C509- Malignant neoplasm of breast of unspecified site
- Registration Number
- CTRI/2023/03/051117
- Lead Sponsor
- ALL INDIA INSTITUTE OF MEDICAL SCIENCES Jodhpur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
1. Written informed consent.
2. Treatment naive metastatic HER2/neu negative breast cancer patients requiring chemotherapy.
3. Age group 18 to 75 years.
4. Eastern Cooperative Oncology Group (ECOG) performance status 0-2.
1. Known case of cardiac diseases (congestive heart failure, Myocardial infarction in past 1 year).
2. Pregnancy and lactating women.
3. Patients with CNS metastasis
4. Known cases of psychiatric illness
5. Patients with Sepsis
6. Clinically relevant peripheral neuropathy
7.Pancytopenia (neutropenia (Absolute neutrophil count < 1.5x109/l), thrombocytopenia (Platelet count <100x109 /l), anemia).
8.Serum creatinine > 2.7 mg/dL & Creatine clearance <30ml
9. Serum total bilirubin > 1.5 times the upper limit of normal
10.ASAT (SGOT) and ALAT (SGPT) > 3x UNL
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method