Clinical Trials/NCT02395952

NCT02395952

Withdrawn

Not Applicable

Comparison of Standard of Care Treatments for Post-operative Non-healing Epithelial Defects

Milton S. Hershey Medical Center1 site in 1 countryMarch 2015

ConditionsCornea

Interventionscarboxymethylcellulose sodium Acuvue Oasys Bandage Contact Lens Prokera Ambiodisk

Drugscarboxymethylcellulose sodium

Overview

Phase: Not Applicable
Intervention: carboxymethylcellulose sodium
Conditions: Cornea
Sponsor: Milton S. Hershey Medical Center
Locations: 1
Primary Endpoint: Abscence of persistent epithelial defect
Status: Withdrawn
Last Updated: 7 years ago

Overview Investigators Eligibility Criteria Arms & Interventions Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of this study is to compare the relative efficacy of four different treatment modalities (i.e. aggressive lubrication, bandage contact lens, Ambiodisk amniotic membrane, Prokera amniotic membrane) in the healing of persistent corneal epithelial defects following retina surgery.

Registry

clinicaltrials.gov

Start Date

March 2015

End Date

February 2018

Last Updated

7 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Milton S. Hershey Medical Center

Responsible Party

Principal Investigator

Principal Investigator

Seth M Pantanelli

Assistant Professor of Ophthalmology

Milton S. Hershey Medical Center

Eligibility Criteria

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Arms & Interventions

Lubrication

Intervention: carboxymethylcellulose sodium

Bandage Contact Lens

Acuvue Oasys Contact Lens

Intervention: Acuvue Oasys Bandage Contact Lens

Prokera

Wet amniotic membrane mounted on plastic retaining ring

Intervention: Prokera

Ambiodisk

Freeze dried amniotic membrane

Intervention: Ambiodisk

Outcomes

Primary Outcomes

Abscence of persistent epithelial defect

Time Frame: 22 days

Secondary Outcomes

Rate of epithelial healing in mm2/day(22 days)
Infection(22 days)

Study Sites (1)

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