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Carboxymethylcellulose

Generic Name
Carboxymethylcellulose
Brand Names
Leader Lubricant Eye Drops, Refresh Drops, Refresh Liquigel, Refresh Optive Advanced, Refresh Optive Extended Therapy, Retaine, Thera Tears, Theratears
Drug Type
Small Molecule
CAS Number
9000-11-7
Unique Ingredient Identifier
05JZI7B19X

Overview

Carboxymethylcellulose is a cellulose derivative that consists of the cellulose backbone made up of glucopyranose monomers and their hydroxyl groups bound to carboxymethyl groups. It is added in food products as a viscosity modifier or thickener and emulsifier. It is also one of the most common viscous polymers used in artificial tears, and has shown to be effective in the treatment of aqueous tear-deficient dry eye symptoms and ocular surface staining . The viscous and mucoadhesive properties as well as its anionic charge allow prolonged retention time in the ocular surface . Sodium carboxymethylcellulose is the most commonly used salt.

Indication

Indicated for the symptomatic relief of burning, irritation and discomfort of the eyes due to dryness or exposure to wind or sun.

Associated Conditions

  • Dry Eyes
  • Ocular Irritation

FDA Drug Approvals

Approved Product
Manufacturer
NDC Code
Route
Strength
Effective Date
No FDA approvals found for this drug.

EMA Drug Approvals

Approved Product
Authorization Holder
Status
Issued Date
No EMA approvals found for this drug.

HSA Drug Approvals

Approved Product
Manufacturer
Approval Number
Dosage Form
Strength
Approval Date
No HSA approvals found for this drug.

NMPA Drug Approvals

Approved Product
Company
Approval Number
Drug Type
Dosage Form
Approval Date
No NMPA approvals found for this drug.

PPB Drug Approvals

Approved Product
Registration No.
Company
Licence No.
Strength
Registration Date
No PPB approvals found for this drug.

TGA Drug Approvals

Approved Product
ARTG ID
Sponsor
Registration Type
Status
Registration Date
No TGA approvals found for this drug.

Health Canada Drug Approvals

Approved Product
Company
DIN
Dosage Form
Strength
Market Date
REFRESH OPTIVE FUSION SENSITIVE
02450534
Solution - Ophthalmic
0.5 % / W/V
4/26/2016
REFRESH OPTIVE GEL DROPS
02463652
Solution - Ophthalmic
1 % / W/V
7/28/2017
REFRESH CELLUVISC
00870153
Drops - Ophthalmic
1 % / W/V
12/31/1991
CLEAR EYES FOR DRY EYES
prestige brands inc
02286858
Solution - Ophthalmic
1.0 %
3/26/2008
REFRESH CONTACTS
02304015
Solution - Ophthalmic
0.5 % / W/V
3/13/2008
PRESERVATIVE-FREE THERA TEARS LUBRICANT EYE DROPS
medtech products inc
02242082
Drops - Ophthalmic
0.25 % / W/V
6/1/2002
NUTRIGEL CAP 300MG
carmaran ltée
00658014
Capsule - Oral
300 MG
12/31/1987
REFRESH OPTIVE ADVANCED SENSITIVE
02425815
Emulsion - Ophthalmic
0.5 % / W/W
10/14/2014
SALIVART AER
all star sales and service ltd.
00894397
Aerosol - Oral
1 %
12/31/1990
REFRESH PLUS
02049260
Drops - Ophthalmic
0.5 % / W/V
1/31/2000

CIMA AEMPS Drug Approvals

Approved Product
Company
Registration Number
Pharmaceutical Form
Prescription Type
Status
No CIMA AEMPS (Spain) approvals found for this drug.

Philippines FDA Drug Approvals

Approved Product
Company
License Number
Dosage Form
Strength
Approval Date
No Philippines FDA approvals found for this drug.

Saudi SFDA Drug Approvals

Approved Product
Company
License Number
Dosage Form
Strength
Approval Date
No Saudi SFDA approvals found for this drug.

Malaysia NPRA Drug Approvals

Approved Product
Company
Registration Number
Dosage Form
Strength
Approval Date
No Malaysia NPRA approvals found for this drug.

UK EMC Drug Information

Medicine Name
MA Holder
MA Number
Pharmaceutical Form
Active Ingredient
Authorization Date
No UK EMC drug information found for this drug.

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