A clinical trial to evaluate the effect of 2 different methods of oxygen supplementation in preventing fall in oxygen saturation during intubation in IC

Not Applicable

Not yet recruiting

• Conditions: Health Condition 1: J40-J47- Chronic lower respiratory diseasesHealth Condition 2: J09-J18- Influenza and pneumoniaHealth Condition 3: J95-J95- Intraoperative and postprocedural complications and disorders of respiratory system, not elsewhere classifiedHealth Condition 4: J20-J22- Other acute lower respiratory infections

• Registration Number: CTRI/2018/09/015747
• Lead Sponsor: Sri Devaraj Urs Academy of Higher Education and Research

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

Patients with Type I (Hypoxemic) respiratory failure, without any hemodynamic compromise.

Hypoxemic respiratory failure is defined as respiratory rate > 30 breaths/min and an FiO2 requirement of 50% or more to obtain oxygen saturation of at least 90%, and PaO2 to FiO2 ratio below 300 mmHg, in the 4 hours before inclusion. Hemodynamic compromise is defined as MAP < 65 mmHg without inotropic support

Exclusion Criteria

1.Patients with anticipated difficult airway as evaluated using MACOCHA score

2.Pregnant or breast feeding woman

3.Contraindications to nasopharyngeal airway insertion like nasopharyngeal obstruction, coagulopathies etc..

4.Contraindications to NIV such as patients with claustrophobia, full stomach and GCS <8 etc..

5.Contraindications to Ketamine and Succinylcholine such as raised intracranial tension, ischemic heart disease, hyperkalemia etc..

Study & Design

• Study Type: Interventional
• Study Design: Not specified