Effectiveness of metformin for metabolic control in obese patients with schizophrenia spectrum and other psychotic disorders - NI

Government Medical College and Hospital Chandigarh0 个研究点目标入组 0 人开始时间: 待定最近更新: 2023年9月18日

研究概览

暂无简介。

•1)Patients with a diagnosis of ‘Schizophrenia spectrum and other psychotic disorders’ as per Diagnostic and Statistical Manual-5(DSM-5).
•2)Patients having the capacity (as per section 4 of Mental Healthcare Act 2017) to give written consent or Nominated Representative (NR)agreeing to give written consent when the patient does not have adequate capacity.
•3)Patients meeting diagnostic criteria for obesity which is specified as Body Mass Index (BMI) of more than 25kg/m² (Consensus statement for Asian Indian guidelines).
•4)Patients on second generation antipsychotics for a minimum duration of 6 months.
•5)Age group 18-65 years
•6)Any gender
•7)Patients able to carry out their normal physical activities

•1)Patients with active substance use disorder within the past 6 months (in terms of fulfilling the ICD-11 criteria for substance dependence) except caffeine and nicotine.
•2)Patients with any acute medical or surgical illness -Diabetes mellitus, impaired renal function, hepatic disease, cardiovascular disorder, thyroid disorder.
•3)Pregnant and lactating patient.
•4)Actively suicidal patients or those having high suicide risk currently.
•5)Patients with eating disorders
•6)Bedridden patients
•7)Current or previous treatment with metformin, or history of hypersensitivity to metformin.
•8)Current or previous treatment with insulin or any other hypoglycaemic agent
•9)Use of any prescription for weight loss prior to study
•10)Patients with history of weight loss in last 6 months

发起方

Government Medical College and Hospital Chandigarh