Effect of Metformin in Acne Vulgaris
Phase 3
- Conditions
- Acne.Acne, unspecifiedL70.9
- Registration Number
- IRCT20201108049309N1
- Lead Sponsor
- Shiraz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
16-40 years old patients with moderate acne .
They should not have been treated with systemic medications since 1 month ago.
They should not have been treated with topical therapy since 2 weeks ago.
Exclusion Criteria
The patients with a history of hypersensitivity to metformin and doxycycline. . Patients with systemic diseases are excluded.
The patients with systemic disease
The pregnant and lactating women
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Acne severity. Timepoint: before treatment and 1,2 months after treatment. Method of measurement: Global acne grading system,burke and cunliffe and counting total lesion count.
- Secondary Outcome Measures
Name Time Method Response to treatment. Timepoint: at the onset and 2 months after treatment. Method of measurement: asking patient himself.;Effect of acne on patient life. Timepoint: before treatment and 2 months after treatment. Method of measurement: Cardiff Acne disability index method.