MedPath

Evaluation of the EZ Blocker

Phase 4
Conditions
Intubation
Thoracic Surgery
One-lung Ventilation
Interventions
Procedure: endotracheal intubation
Registration Number
NCT01171560
Lead Sponsor
Medical University of Vienna
Brief Summary

In anesthetized patients the airway needs to be secured due to lack of protective reflexes. Golden standard is the endotracheal intubation. In patients undergoing lung surgery single lung ventilation is essential. In these cases a double lume tube is commonly used. The double lume tube has a proximal tracheal and a distal bronchial end reaching into the left or the right side of the lung dependant of the model of the tube. Thus it is possible to operate on one collapsed side of the lung while ventilating the other side.

Due to length and stiffness resulting of the construction of the device more side effects than after intubation with a conventional single lumen tube is expected. Possible side effects may be bleeding, swelling, sore throat or croakiness.

The EZ-Blocker is a new device promising to overcome these side effects. The EZ-Blocker is a device placing a balloon into one bronchus to be able to provide single lung ventilation like the double lume tube. However, the EZ-Blocker is a catheter pushed through a conventional single lume tube after intubation with a hook on one and a balloon on the other distal end. The hook prevents the device from being pushed too far to be able to harm the lung. Inside the EZ-Blocker is a small lumen able to deflate the lung which is blocked with the balloon. The device is easily positioned using a bronchoscope and when the anaesthesiologists confirmed the correct position of the device, the balloon can be inflated and deflated as needed.

Due to the easier approach the investigators expect less side effects as mentioned earlier using the EZ-Blocker compared to the double lume tube. As well the stress caused by intubation may be reduced.

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
40
Inclusion Criteria
  • Elective surgery
  • thoracic surgery with requiring single lung ventilation in lateral position
  • ASA Status 1-3
  • Oral and written consent to participation
  • Age 18- 90
Exclusion Criteria
  • Contraindications against placing a double lume tube, like tracheal lesions, etc.
  • Thoracic surgery within the last four weeks
  • Any form of infection (Pneumonia, Pleural empyema) or suspected Tbc
  • BMI higher than 45
  • Patients with a previous diagnoses or suspected difficult airway

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
EZ Blockerendotracheal intubationPatients assigned to the EZ group will be intubated using a conventional tube in an adequate size as it is standard of care and single lung ventilation will be provided using the EZ-Blocker.
Double lumen tubeendotracheal intubationThe patients assigned to the "double lume tube" group will be intubated using the double lume tube in an adequate size as it is standard of care.
Primary Outcome Measures
NameTimeMethod
Time from intubation to ventilation:5 minutes

is intubation and achieving lung separation faster using a conventional double-lung-tube or using the EZ-Blocker ?

Secondary Outcome Measures
NameTimeMethod
postoperative sore throat or croakiness2 minutes

Documentation of sore throat and croakiness by questioning the patients the day after surgery

resistance to dislocation10 minutes

Which device, double-lung-tube or EZ-Blocker, is more resistant to dislocation in endotracheal/endobronchial position, especially when the patient is moved from dorsal to lateral position?

Peripheral oxygen saturation (SpO2)3 hours

Decrease of Peripheral oxygen saturation (SpO2) (in min) under 90% during the hole surgery

Trial Locations

Locations (1)

General Hospital of Vienna

🇦🇹

Vienna, Austria

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