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Clinical Trials/NCT01149772
NCT01149772
Completed
Not Applicable

Cognitive Behavioral Therapy in Primary Care: Treating the Medically Ill

VA Office of Research and Development2 sites in 1 country302 target enrollmentFebruary 2011

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Chronic Obstructive Pulmonary Disease
Sponsor
VA Office of Research and Development
Enrollment
302
Locations
2
Primary Endpoint
Beck Anxiety Inventory (BAI)
Status
Completed
Last Updated
10 years ago

Overview

Brief Summary

The current study seeks to test the effectiveness of a talk-therapy intervention designed to better meet the needs of chronically ill Veterans. This project looks to recruit 450 Veterans with either chronic obstructive pulmonary disease (COPD) or heart failure (HF) who also have symptoms of worry, stress, anxiety, or sadness. Participants will be randomly put into either the talk-therapy intervention or enhanced usual care.

The talk therapy intervention will be provided by VA clinicians in the primary care setting and will consist of 6 core meetings (30-45 minutes in duration) and 2 follow-up telephone meetings. Enhanced usual care participants will receive feedback regarding the assessment findings and educational materials on COPD and/or HF, depression and anxiety.

Detailed Description

Diseases of the heart and circulatory system, namely, Chronic Obstructive Pulmonary Disease (COPD) and Heart Failure (HF), are two of the most common and disabling chronic diseases. Both COPD and HF account for significant disability, mortality, and healthcare costs and are associated with lower health status and more functional and social limitations than other chronic illnesses, such as hypertension and diabetes. As our population ages and life span increases, the numbers of patients with these conditions and the subsequent healthcare costs will increase dramatically. The symptoms associated with COPD and HF can significantly affect daily functioning. Physical symptoms are often linked to increased levels of psychological distress, namely, anxiety and depression, which significantly affect quality of life and functioning above and beyond the impact of the medical disease. As depression and anxiety are modifiable clinical factors, there is a potential to significantly alter patient outcomes, as well as use of healthcare services. However, focused interventions are needed, given the high risk for poor mental health treatment and underuse of mental health services in persons with COPD and HF. Unfortunately, few intervention studies have been conducted in medically ill patients with these conditions. The current project will examine whether existing VA clinicians in the primary care setting, with training and support, can effectively administer a structured Cognitive Behavioral Therapy (CBT) intervention for depressed and anxious Veterans with COPD and HF.

Registry
clinicaltrials.gov
Start Date
February 2011
End Date
October 2014
Last Updated
10 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • COPD and/or HF diagnosis; confirmation based upon medical chart review.
  • clinically significant symptoms for anxiety and/or depression.

Exclusion Criteria

  • cognitive impairment
  • presence of bipolar, psychotic or substance abuse disorder.

Outcomes

Primary Outcomes

Beck Anxiety Inventory (BAI)

Time Frame: 4 month (post treatment), 8 month follow/up, and 12 month follow/up

The BAI measures an individual's level of anxiety. The measure is summed and ranges from 0 - 63 (individual item score range 0 -3 per 21 items); were higher scores = worse symptoms.

Chronic Respiratory Questionnaire_Fatigue

Time Frame: 4 month (post treatment), 8 month follow/up, 12 month follow/up

The Chronic Respiratory Questionnaire (CRQ) measures the quality of life of patients with a chronic respiratory disease. This subscale measures the amount of fatigue patients experience with the condition. The CRQ is a mean score and ranges from 1 - 7, where a higher score = better health.

Patient Health Questionnaire -9 (PHQ-9)

Time Frame: 4 month (post treatment), 8 month follow/up, and 12 month follow/up

The PHQ-9 measures an individual's level of depression. The measure is summed and ranges from 0 - 27 (individual item score range 0 - 3 per 9 items); where higher scores = worse symptoms.

Chronic Respiratory Questionnaire_Mastery

Time Frame: 4 month (post treatment), 8 month follow/up, 12 month follow/up

The Chronic Respiratory Questionnaire (CRQ) measures the quality of life of patients with a chronic respiratory disease. The subscale Mastery looks at the patient's perceived control over the condition. The CRQ is a mean score and ranges from 1 - 7, where a higher score = better health

Chronic Respiratory Questionnaire_Dyspnea

Time Frame: 4 month (post treatment), 8 month follow/up, 12 month follow/up

The Chronic Respiratory Questionnaire (CRQ) measures the quality of life of patients with a chronic respiratory disease. The subscale Dyspnea looks at how much shortness of breath a patient experiences. The CRQ is a mean score and ranges from 1 - 7, where a higher score = better health.

Kansas City Cardiomyopathy Questionnaire (KCCQ)

Time Frame: 4 month (post treatment), 8 month follow/up, and 12 month follow/up

The KCCQ measures the health status of patients with congestive heart failure. The overall score is a mean score scaled from 0 - 100; where 0 represents most severe/limited functioning.

Study Sites (2)

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