Effectiveness of Cognitive Behavioral Therapy in Patients With End-Stage Renal Disease in Hemodialysis and With Depression
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Depression
- Sponsor
- Federal University of São Paulo
- Enrollment
- 80
- Locations
- 1
- Primary Endpoint
- Mini International Neuropsychiatric Interview (MINI-DSM-IV) Beck Depression Inventory (BDI)
- Last Updated
- 18 years ago
Overview
Brief Summary
The purpose of this study is to determine whether Cognitive Behavioral Therapy is effective in the treatment of depression in patients with end-stage renal disease in hemodialysis therapy
Detailed Description
Depression is a persistent problem among patients with end-stage renal disease and it does not tend to improve over time. The implementation of effective interventions to treat and prevent recurrence of depressive episodes is needed. The objectives of this study are: 1)the detection of Major Depression in hemodialysis patients; 2)to allocate patients with depression in two groups: structured program of treatment with CBT (group therapy)and control group (conventional psychotherapy at the dialysis unit); and 3)to verify whether after 3 months of CBT there was a remission of depressive symptoms and a improvement of the quality of life in the CBT group.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients with a diagnosis of Chronic renal disease (end stage) in hemodialysis for at least 3 months
- •Diagnosis of Major depression disorder (4 or more clinical criteria in MINI and a BDI score of 10 or more)
Exclusion Criteria
- •Patients in process of renal transplant with (living donor)
- •Psychiatric comorbidity
- •Cognitive impairment or mental retardation
- •Current substance abuse
- •Heart failure, angina pectoris, arrhythmias
Outcomes
Primary Outcomes
Mini International Neuropsychiatric Interview (MINI-DSM-IV) Beck Depression Inventory (BDI)
Time Frame: Baseline; 3 months (end of intervention); follow-up (6 months after the end of the intervention)
Secondary Outcomes
- Kidney Disease and Quality of Life Short-form (KDQOL-SF)(Baseline; 3 months (end of intervention); follow-up (6 months after the end of the intervention))