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Clinical Trials/NCT01431235
NCT01431235
Completed
N/A

Investigating the Efficacy of Cognitive Behavioral Therapy in Patients With Substance Use Disorder and Comorbid ADHD. A Randomized Controlled Trial With Cognitive Behavioral Therapy

Arkin1 site in 1 country184 target enrollmentAugust 2011

Overview

Phase
N/A
Intervention
Not specified
Conditions
Attention Deficit Hyperactivity Disorder
Sponsor
Arkin
Enrollment
184
Locations
1
Primary Endpoint
self reported ADHD symptoms
Status
Completed
Last Updated
9 years ago

Overview

Brief Summary

The purpose of this study is to determine if cognitive behavioral therapy is effective in treating ADHD symptoms in patients with substance use disorders and comorbid ADHD.

Detailed Description

Attention Deficit Hyperactivity Disorder(ADHD) is an important comorbid condition in patients with substance use disorders (SUD). The prevalence of ADHD in patients with SUD is estimated 23%, and ADHD is associated with an untoward prognosis of SUD. However, adequate treatment programs for patients with ADHD and SUD are not available. Results of medication trials for patients with ADHD and SUD are disappointing, and cognitive behavioral therapy (CBT) has not yet been investigated in this population. In patients with ADHD without comorbid SUD, the results of CBT in randomized trials are positive. The purpose of this study is to investigate if CBT is effective in treating ADHD symptoms in patients with ADHD and SUD.

Registry
clinicaltrials.gov
Start Date
August 2011
End Date
December 2016
Last Updated
9 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Arkin
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • substance use disorder
  • able to comply with study activities

Exclusion Criteria

  • severe neurological or psychiatric diseases (for example Parkinson, dementia, psychosis, bipolar depression) which require medication
  • unable to read or write Dutch language

Outcomes

Primary Outcomes

self reported ADHD symptoms

Time Frame: 6 months

Dutch self report list of ADHD symptoms by Kooij and Buitelaar

Secondary Outcomes

  • TIC-P(6 months)
  • Stroop task(6 months)
  • Time Line Follow Back method(6 months)
  • EQ-5(6 months)
  • Beck Anxiety Inventory(6 months)
  • urine checks(6 months)
  • BART task(6 months)
  • Beck depression inventory(6 months)
  • Tower of London task(6 months)

Study Sites (1)

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