CBT for Patients With Attention Deficit Hyperactivity Disorder (ADHD) and Substance Use Disorders

Not Applicable

Completed

• Conditions: Attention Deficit Hyperactivity Disorder; Substance Use Disorders
• Interventions: Behavioral: cognitive behavioral therapy for treating ADHD symptoms

• Registration Number: NCT01431235
• Lead Sponsor: Arkin

Brief Summary

The purpose of this study is to determine if cognitive behavioral therapy is effective in treating ADHD symptoms in patients with substance use disorders and comorbid ADHD.

Detailed Description

Attention Deficit Hyperactivity Disorder(ADHD) is an important comorbid condition in patients with substance use disorders (SUD). The prevalence of ADHD in patients with SUD is estimated 23%, and ADHD is associated with an untoward prognosis of SUD. However, adequate treatment programs for patients with ADHD and SUD are not available. Results of medication trials for patients with ADHD and SUD are disappointing, and cognitive behavioral therapy (CBT) has not yet been investigated in this population. In patients with ADHD without comorbid SUD, the results of CBT in randomized trials are positive. The purpose of this study is to investigate if CBT is effective in treating ADHD symptoms in patients with ADHD and SUD.

Study Timeline

• Study Start: 2011-08
• Study First Submitted: 2011-09-08
• Study First Submitted QC: 2011-09-08
• Study First Posted: 2011-09-09
• Primary Completion: 2016-12
• Study Completion: 2016-12
• Status Verified: 2017-01
• Last Update Submitted: 2017-01-13
• Last Update Posted: 2017-01-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 184

Inclusion Criteria

• substance use disorder
• ADHD
• able to comply with study activities

Exclusion Criteria

• severe neurological or psychiatric diseases (for example Parkinson, dementia, psychosis, bipolar depression) which require medication
• unable to read or write Dutch language

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
addiction treatment and ADHD treatment	cognitive behavioral therapy for treating ADHD symptoms	10 sessions cognitive behavioral therapy on addiction treatment combined with 5 sessions on ADHD treatment.

Primary Outcome Measures

Name	Time	Method
self reported ADHD symptoms	6 months	Dutch self report list of ADHD symptoms by Kooij and Buitelaar

Secondary Outcome Measures

Name	Time	Method
TIC-P	6 months	health care consumption and production loss in relation to mental health problems
Stroop task	6 months	neuropsychological measure
Beck Anxiety Inventory	6 months	Self reported anxiety symptoms
Time Line Follow Back method	6 months	self-reported alcohol and drug use
EQ-5	6 months	Self reported quality of living
urine checks	6 months	urine checks on drug use
BART task	6 months	neuropsychological task on risk taking behavior
Beck depression inventory	6 months	self reported depression symptoms
Tower of London task	6 months	neuropsychological task

Trial Locations

Locations (1)

Arkin; 🇳🇱 Amsterdam, Netherlands