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Clinical Trials/NCT03112759
NCT03112759
Completed
Not Applicable

Assessing the Utility of Cognitive Behavioral Therapy for Pain Control in Patients With Chronic Pancreatitis

University of Louisville1 site in 1 country9 target enrollmentSeptember 9, 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Chronic Pancreatitis
Sponsor
University of Louisville
Enrollment
9
Locations
1
Primary Endpoint
Presence and severity of abdominal pain
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

This study will assess cognitive behavioral therapy as an adjunct to conventional symptom control for patients with chronic pancreatitis.

Detailed Description

All patients with chronic pancreatitis will be considered for participation in this study. Patients selected for participation will be evaluated 4 weeks prior to the first one-on-one therapy session. A baseline pain score will be assessed using the visual analog pain scale. Narcotic dosage and frequency as well as anti-emetic usage will be evaluated at this time. A pre-treatment quality of life score will be recorded using the SF-12® Patient Questionnaire. Patients will also be queried about the presence of nausea and reflux. After the pre-intervention evaluations are complete, patients will be randomized into one of two arms: treatment with cognitive behavioral therapy and narcotics as needed or treatment with conventional narcotic analgesics alone. Patients undergoing CBT intervention will participate in eight weekly therapy sessions. Follow-up assessments will be conducted six months and nine months after the last therapy session is completed. The patients will be evaluated based on pain score, narcotic dosage and frequency, anti-emetic usage, quality of life assessment, and pain related hospitalizations.

Registry
clinicaltrials.gov
Start Date
September 9, 2017
End Date
March 26, 2020
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Gary C. Vitale, MD

General Surgeon, Professor of medicine

University of Louisville

Eligibility Criteria

Inclusion Criteria

  • Patient must be18 years of age
  • Diagnosed with chronic pancreatitis
  • Willing and able to comply with the protocol requirements
  • Able to comprehend and have signed the Informed Consent Form (ICF) to participate in the study

Exclusion Criteria

  • Participating in another clinical trial for the treatment of chronic pancreatitis at the time of screening

Outcomes

Primary Outcomes

Presence and severity of abdominal pain

Time Frame: 1 year

A visual analog scale will be used to measure patients pain pre- and post- intervention

Secondary Outcomes

  • Quality of Life(1 year)
  • Narcotic Usage(1 year)
  • Presence and Severity of Nausea and Reflux(1 year)
  • Hospitalizations(1 year)

Study Sites (1)

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