ebulising Amoxicillin-Clavulanic Acid in Patients with COPD.
Suspended
- Conditions
- COPDexacerbationnebulizationinhalationamoxicillin
- Registration Number
- NL-OMON22557
- Lead Sponsor
- Dr. P.D.L.P.M. van der Valk
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Suspended
- Sex
- Not specified
- Target Recruitment
- 30
Inclusion Criteria
1. A clinical diagnosis of COPD, as defined by GOLD criteria;
2. Admitted with signs and symptoms of an exacerbation of COPD, defined as an acute negative change from the baseline, reported by the patient, in dyspnoea and/or sputum volume and/or colour of sputum (yellowish or greenish sputum) and/or cough;
Exclusion Criteria
1. Current treatment with amoxicillin or amoxicillin clavulanic acid;
2. Impaired renal function (GFR < 30);
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Sputum concentration of amoxicillin at day 3.
- Secondary Outcome Measures
Name Time Method Time of hospitalization.