The Effect of Adiponectin-Leptin Ratio on Weight Loss in Patients Undergoing Sleeve Gastrectomy Due to Morbid Obesity
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 78
- 试验地点
- 1
- 主要终点
- Change in body mass index at 8 months
研究概览
简要总结
The study aims to find out if a specific blood test, measuring the balance between two hormones (adiponectin and leptin), can predict how much weight a person might lose after sleeve gastrectomy, a surgery for obesity. The investigators want to see if this hormone ratio can help identify who will benefit most from the surgery. If the investigators find that people with a low hormone ratio are less likely to lose weight after surgery, doctors can guide them toward other weight-loss options, like lifestyle changes or different treatments, instead of surgery. This way, patients can get the care that's best for them.
详细描述
The subject of the research is to investigate whether preoperative adiponectin-leptin ratios are predictive of weight loss in patients undergoing sleeve gastrectomy for morbid obesity. If the study finds the adiponectin-leptin ratio to be a significant predictor of weight loss, individuals with a low preoperative ratio, which are expected to lose less weight following surgery, can be redirected to more suitable treatment options other than sleeve gastrectomy. This will allow patients less likely to benefit from surgery to be guided toward conservative approaches.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged 18 to 75
- •International Classification of Diseases (ICD) code E66 diagnosis (obesity)
- •Patients who have given consent for sleeve gastrectomy
- •Patients who are suitable for general anesthesia
排除标准
- •Patients who did not give consent to be included in the study
- •Patients who are scheduled for surgery other than sleeve gastrectomy
研究组 & 干预措施
Sleeve Gastrectomy Patients
Patients who meet inclusion criteria for the study undergoing sleeve gastrectomy
干预措施: Laparoscopic Sleeve Gastrectomy (Procedure)
结局指标
主要结局
Change in body mass index at 8 months
时间窗: 8 months after surgery
次要结局
- Change in lipid profile at 8 months(8 months after surgery)
研究者
Sercan YUKSEL, MD
Associate Professor
Başakşehir Çam & Sakura City Hospital