Comparison of Efficacy Between Silicone Ahmed Glaucoma Valves With and Without Intravitreal Triamcinolone Injection
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 49
- 试验地点
- 2
- 主要终点
- intra ocular pressure after the surgery in both groups
研究概览
简要总结
The management of neovascular glaucoma (NVG) is a challenge for the ophthalmologist and surgery is frequently needed to control IOP. The success rates of a drainage device is usually lower in NVG than in other forms of glaucoma. Triamcinolone intra-vitreous injections acetate has been used to treat macular edema secondary to diabetic retinopathy and central retinal vein occlusion and also to control inflammation in ophthalmologic surgeries.
In the present study we will compare the outcome and complications of Silicone Ahmed Valve in GNV eyes with and without intra-vitreous triamcinolone injection.
详细描述
The management of neovascular glaucoma (NVG) is a challenge for the ophthalmologist and surgery is frequently needed to control intraocular pressure (IOP). The success rates of a drainage device is usually lower in NVG than in other forms of glaucoma. Triamcinolone intra-vitreous injections acetate has been used to treat macular edema secondary to diabetic retinopathy and central retinal vein occlusion and also to control inflammation in ophthalmologic surgeries.
In the present study we will compare the outcome and complications of Silicone Ahmed Valve in GNV eyes with and without intra-vitreous triamcinolone injection.
49 Patients with clinically uncontrolled neovascular glaucoma were selected from the glaucoma sector of Federal university of Sao Paulo. After retinal panfotocoagulation (RPF), patients who still are uncontrolled are enrolled to the study. Patients were randomized to one of two groups:
- Silicone Ahmed Implant
- Silicone Ahmed Implant with intra-vitreous Triamcinolone injection
Inclusion Criteria:
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with NVG and uncontrolled IOP despite the use of maximum tolerated glaucoma medication
- •Patients over 18 years old.
- •Patients who can understand and sign the inform consent form.
排除标准
- •Active Sclerites
- •Uveitic Neovascular glaucoma
- •Previous psiquiatric condition
- •Patients who can understand and sign the inform consent form
- •Visual acuity worse than hand motion
- •Previous retina surgery with buckle implant
结局指标
主要结局
intra ocular pressure after the surgery in both groups
时间窗: monthly
次要结局
- complication rates after surgery(monthly)