Examining the effect of superior vs temporal laser peripheral iridotomy in adults with primary angle-closure glaucoma or angle-closure suspect

Not Applicable

• Conditions: primary angle-closure glaucoma; primary angle-closure suspect; Eye - Diseases / disorders of the eye

• Registration Number: ACTRN12622000737730
• Lead Sponsor: Rachel Xuan

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-05-23
• Last Update Posted: 30 May 2022

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 138

Inclusion Criteria

1) Participants (>18 years old) diagnosed with primary angle closure glaucoma or primary angle-closure suspect in both eyes and requiring laser peripheral iridotomy intervention
2) Participants are able to attend required study visits

Exclusion Criteria

1) Participants who have undergone previous laser peripheral iridotomy procedure in either eye
2) Participants who have undergone previous intraocular surgery
3) Participants with asymmetrical ptosis of more than 2mm
4) Participants with any active intraocular inflammation at the time of undergoing laser peripheral iridotomy procedure
5) Participants with a history of acute-attack angle closure glaucoma

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The presence of dysphotopsia symptoms will be self-reported by participants using a standardised questionnaire at follow up appointments. The questionnaire is designed specifically for this study. [1 month and 6 months post-procedure]

Secondary Outcome Measures

Name	Time	Method
aser parameters including iridotomy hole size (in mm), number of shots used, and total laser energy used (kJ) will be documented during the procedure as per procedure protocol. An audit of study records will be performed retrospectively to collect this data. <br><br>[Intraoperative<br>];Post-procedure intraocular pressure (IOP) using tonometer[Pre-procedure, at 1 month and 6 months post-procedure];Incidence of post-procedure complications including transient post-op increase in IOP (using tonometer), iris bleeding (assessed by slit lamp examination) and occluded LPIs (determined by post-procedure IOP measured using tonometer) post-procedure requiring repeat LPI[1 month and 6 months post-procedure];Visual acuity using Snellen Chart[Pre-procedure, 1 month and 6 months post-procedure]