Investigation of imaging and neuropsychological biomarkers for aggressive behavior during therapy with the anticonvulsants levetiracetam and perampanel.
- Conditions
- G40Epilepsy
- Registration Number
- DRKS00030739
- Lead Sponsor
- niversitätsklinikum der RWTH Aachen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 140
Inclusion Criteria
Patients with a confirmed diagnosis of epilepsy aged 18-70 years. Furthermore, age-matched controls without neurological or other severe diseases should be recruited.
Exclusion Criteria
Participants are excluded if they are not admissible to MRI.
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Changes in neuropsychological and brain functional characteristics of patients during treatment and after discontinuation of levetiracetam and perampanel, respectively. (FMRI, OASM, BDI, BIS, ASQ, EpiTrack, BPAQ, SCID-V)
- Secondary Outcome Measures
Name Time Method Tolerability of side effects