ltra-sensitive detection of the T790M mutation using droplet digital PCR and, efficacy and resistance analysis of EGFR tyrosine kinase inhibitors in pretreatment non-small cell lung cancer patients with EGFR mutation.
Not Applicable
Completed
- Conditions
- on-small cell lung cancer
- Registration Number
- JPRN-UMIN000027592
- Lead Sponsor
- Osaka City University Graduate School of Medicine Department of Respiratory Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 74
Inclusion Criteria
Not provided
Exclusion Criteria
none
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The association between the quantity of T790M copies and progression free survival of EGFR tyrosine kinase inhibitor treatment
- Secondary Outcome Measures
Name Time Method The association between the quantity of T790M copies and response rate or overall survival The association between efficacy of EGFR tyrosine kinase inhibitor mutations such as CTNNB1 and MET amplification Compare T790M detection using Cobas V2.0 and degital droplet PCR