CTRI/2016/02/006677招募中不适用
Effects of chemotherapy on cognition in cancer patients: an observational study.
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- Assesment of neurobehaviour in cancer patients by validated questionnaire
研究概览
简要总结
Patients undergoing chemotherapy for various kinds of cancer were assessed for cognitive assessment at three cycles of chemotherapy using MMSE score. Discarded blood samples were collected after each cycle for inflammation assessment using ELISA. Its an observational study to find out the correlation between cognition and inflammation by chemotherapy
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 55.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Patient must have histologically and cytologically confirmed cancer.
- •2.Patient receiving chemotherapy for the treatment of cancer.
- •3.Both males and female patients.
- •4.Patient capable of giving informed consent 5.Patient willing to participate in the study.
排除标准
- •1.History of cognitive impairment and Alzheimer’s disease.
- •2.History of head injury 3.Patients had evidence of uncontrolled clinical diseases, including diabetes, rheumatologic diseases, asthamatic diseases or other chronic inflammatory conditions.
- •4.Patient having brain cancer.
- •5.Patient having neuropsychiatric disorders.
- •6.On any psychotropic medications.
- •7.History of schizophrenia and other neurological and neurobehavioural diseases.
- •9.Using any concurrent medication like Donepezil, rivastigmine, galantamine, Memantine Tacrine cholinergic drugs.
- •10.Patient using anti inflammatory drugs.
- •11.Alcoholics.
- •12.Incompetent for interview.
结局指标
主要结局
Assesment of neurobehaviour in cancer patients by validated questionnaire
时间窗: 1 day before 1st, 2nd and 3rd and 4th cycle of chemotherapy
次要结局
- assesment of socioeconomic status of patient using questionnire(NA)
研究者
研究点 (1)
Loading locations...
相似试验
招募中
不适用
Chemotherapy-induced Cognitive and Brain Changes in Older Adults With Breast CancerImpaired CognitionChemo-brainBreast CancerNCT02290834Massachusetts General Hospital200
招募中
不适用
Effects of chemotherapy on neurobehaviour of cancer patients:an observational studyCTRI/2016/02/006677Jamia Hamdard300
已完成
不适用
The influence of chemotherapy on cognitive function and psychiatric symptoms in patients with breast cancerBreast cancerJPRN-UMIN000016282Institute of Health Biosciences, The University of Tokushima Graduate School20
已完成
不适用
Cognitive Changes in Adult Cancer SurvivorsCognitive ImpairmentEffects of ChemotherapyNCT01569932Washington University School of Medicine13
Unknown
不适用
Chemotherapy Effect on Brain Structure, Neurophysiology and Psychomotor Behavior in Breast Cancer PatientsBreast CancerNCT02896504Kessler Foundation60