An Analysis of Dermabond vs. Non-Absorbable Sutures in Skin Closure for Brow Ptosis Procedures

Not Applicable

Completed

• Conditions: Brow Ptosis; Surgical Wound
• Interventions: Device: Dermabond; Other: Non-Absorbable Sutures

• Registration Number: NCT05981443
• Lead Sponsor: Cody Blanchard

Brief Summary

The goal of this clinical trial is to compare Dermabond with non-absorbable sutures in skin closure after brow ptosis surgery. The main questions it aims to answer are:

* if Dermabond provides equivalent wound healing compared to conventional non-absorbable skin suture techniques

* if Dermabond provides equivalent scar appearance compared to conventional non-absorbable suture techniques

* if Dermabond results in equivalent complication rates compared to conventional non-absorbable suture techniques Participants will have be randomly selected to have either Dermabond or non-absorbable suture closure methods. Scar analysis and both participant and provider surveys will be performed to assess the differences between groups, if any.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-07-31
• Study First Submitted QC: 2023-07-31
• Study First Posted: 2023-08-08
• Study Start: 2023-08-15
• Primary Completion: 2024-04-17
• Study Completion: 2024-04-17
• Results First Submitted: 2025-03-31
• Status Verified: 2025-04
• Results First Submitted QC: 2025-04-21
• Last Update Submitted: 2025-04-21
• Results First Posted: 2025-04-24
• Last Update Posted: 2025-04-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 8

Inclusion Criteria

• Patients undergoing bilateral direct excision brow lift for brow ptosis at the University of Kentucky Medical Center.
• Patients > 18 years of age.
• Patients must be able to follow up at the specified intervals.
• Patients who are able to give their own informed consent.
• Health Status: Variable health status reflective of general population of Kentucky. Patients will be healthy enough to be seen in an office setting.
• All patients will need to be proficient in the English language to understand the scale used for scar assessment

Exclusion Criteria

• Patients <18 years of age or >100
• Allergy to Dermabond
• Adults with impaired consent capacity
• Incarcerated individuals

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Active Comparator: Dermabond	Dermabond	The surgical wound over one eyebrow will be closed with Dermabond.
Active Comparator: Non-Absorbable Sutures	Non-Absorbable Sutures	The surgical wound over one eyebrow will be closed with non-absorbable sutures.

Primary Outcome Measures

Name	Time	Method
Number of Participants With Complications	6 weeks	Complications of both Dermabond and non-absorbable sutures to include dehiscence and infection
Scar Appearance	6 weeks	Patient and Observer Scar Assessment Scale filled out by both patient and provider at both postoperative visits of both Dermabond and non-absorbable sutures. This survey is scaled from 0-10, with 0 being normal skin and 10 being very different skin. Lower scores are desired on this survey.

Trial Locations

Locations (1)

University of Kentucky; 🇺🇸 Lexington, Kentucky, United States