A Study to Evaluate the Safety and Efficacy of mRNA-1345 Vaccine Targeting Respiratory Syncytial Virus (RSV) in Adults ≥60 Years of Age
- Conditions
- Respiratory Syncytial Virus
- Interventions
- Drug: PlaceboDrug: mRNA-1345
- Registration Number
- NCT05127434
- Lead Sponsor
- ModernaTX, Inc.
- Brief Summary
The main purpose of Part A of this study is to evaluate the safety and tolerability of mRNA-1345 vaccine and to demonstrate the efficacy of a single dose of mRNA-1345 vaccine in the prevention of a first episode of RSV-associated lower respiratory tract disease (RSV-LRTD) as compared with placebo from 14 days postinjection through 12 months.
The main purpose of Part B of this study is to evaluate the safety, tolerability and immunogenicity of a booster dose (BD) of mRNA-1345 administered 24 months after the primary dose.
- Detailed Description
The study will be conducted in 2 phases: Phase 2 and Phase 3. In the Part A Phase 2 segment, up to 2,000 participants will be randomly assigned to receive a single injection of either mRNA-1345 vaccine at the selected dose or placebo in a 1:1 randomization ratio.
In the Part A Phase 3 segment, approximately 35,000 participants will be randomly assigned to receive a single injection of either mRNA-1345 vaccine at the selected dose or placebo in a 1:1 randomization ratio.
In the Part B substudy, 1500 participants who received a dose of mRNA-1345 in Part A Phase 3 will be randomly assigned in a 2:1 randomization ratio to receive a single BD injection of either mRNA-1345 at the selected dose or placebo.
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 36814
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Placebo Placebo Single injection of mRNA-1345 matching-placebo on Day 1. mRNA-1345 mRNA-1345 Single injection of mRNA-1345 on Day 1. mRNA-1345 BD mRNA-1345 Single injection of mRNA-1345 on BD Day 1.
- Primary Outcome Measures
Name Time Method Number of Participants with Solicited Local and Systemic Adverse Reactions (ARs) Up to 7 days after each injection Number of Participants with Unsolicited Adverse Events (AEs) Up to 28 days after each injection Vaccine Efficacy (VE) of mRNA-1345 to Prevent a First Episode of RSV-LRTD with 2 or More Symptoms From 14 days postinjection up to 12 months postinjection VE of mRNA-1345 to prevent reverse transcription polymerase chain reaction (RT-PCR) confirmed protocol-defined RSV-LRTD, defined as 100\*(1-HR ratio), where HR is the hazard ratio (mRNA-1345 versus placebo).
Geometric Mean Titer (GMT) of Serum Respiratory Syncytial Virus Subtype A (RSV-A) and Respiratory Syncytial Virus Subtype B (RSV-B) Neutralizing Antibodies BD Day 29 Number of Participants With Medically Attended AEs (MAAEs), Adverse Events of Special Interests (AESIs), Serious Adverse Events (SAEs), and AEs Leading to Withdrawal Up to BD Day 181 VE of mRNA-1345 to Prevent a First Episode of RSV-LRTD with 3 or More Symptoms From 14 days postinjection up to 12 months postinjection VE of mRNA-1345 to prevent reverse transcription polymerase chain reaction (RT-PCR) confirmed protocol-defined RSV-LRTD, defined as 100\*(1-HR ratio), where HR is the hazard ratio (mRNA-1345 versus placebo).
Geometric Mean Ratio (GMR) of Serum RSV-A and RSV-B Neutralizing Antibodies After BD Compared to After Initial Dose BD Day 29
- Secondary Outcome Measures
Name Time Method GMT of Serum RSV Neutralizing Antibodies Baseline through up to 24 months postinjection Geometric Mean Concentration (GMC) of Serum RSV Binding Antibodies Baseline through up to 24 months postinjection GMFR of Serum RSV-A and RSV-B Neutralizing Antibodies from Pre-primary Dose (Baseline) Baseline, BD Day 1, Day 29 and Day 181 VE of mRNA-1345 to Prevent First Hospitalization Associated with RSV-ARD or RSV-LRTD From 14 days postinjection up to 12 months postinjection VE of mRNA-1345 to prevent first hospitalization associated with RSV-ARD or RSV-LRTD, defined as 100\*(1-HR ratio), where HR is the hazard ratio (mRNA-1345 versus placebo).
Proportion of Participants with ≥4-fold Increases in Antibody Titers from Baseline Baseline through up to 24 months postinjection Seroresponse Rate (SRR) Difference Between Serum RSV-A and RSV-B Neutralizing Antibodies After BD Compared to After Initial Dose BD Day 29 GMT of Serum RSV-A and RSV-B Neutralizing Antibodies BD Day 1 and Day 181 VE of mRNA-1345 to Prevent a First Episode of RSV-Associated Acute Respiratory Disease (RSV-ARD) From 14 days postinjection up to 12 months postinjection VE of mRNA-1345 to prevent RT-PCR confirmed protocol-defined RSV-ARD, defined as 100\*(1-HR ratio), where HR is the hazard ratio (mRNA-1345 versus placebo).
Seroresponse Rate in RSV Neutralizing Antibodies Baseline through up to 24 months postinjection Geometric Mean Fold-Rise (GMFR) of Postbaseline/Baseline Antibody Titers Baseline through up to 24 months postinjection SRR of Serum RSV-A and RSV-B Neutralizing Antibodies from Pre-primary Dose (Baseline) Baseline, BD Day 1, Day 29 and Day 181
Trial Locations
- Locations (266)
HEALOR Primary Care - Physicians Las Vegas - CCT
🇺🇸Las Vegas, Nevada, United States
Velocity Clinical Research - Cincinnati - PPDS
🇺🇸Cincinnati, Ohio, United States
AES - DRS - Synexus Clinical Research US, Inc. - Cincinnati
🇺🇸Cincinnati, Ohio, United States
Lakeview Clinical Research
🇺🇸Guntersville, Alabama, United States
Desert Clinical Research, LLC - CCT
🇺🇸Mesa, Arizona, United States
AES - DRS - Optimal Research Alabama - Huntsville
🇺🇸Huntsville, Alabama, United States
Hope Research Institute LLC - Hunt - PPDS
🇺🇸Hunt, Arizona, United States
Tucson Neuroscience Research - M3 WR
🇺🇸Tucson, Arizona, United States
Velocity Clinical Research, Banning
🇺🇸Banning, California, United States
Hope Clinical Research, LLC
🇺🇸Canoga Park, California, United States
Baptist Health Center for Clinical Research
🇺🇸Little Rock, Arkansas, United States
Velocity Clinical Research - Chula Vista - PPDS
🇺🇸Chula Vista, California, United States
Velocity Clinical Research, San Diego
🇺🇸La Mesa, California, United States
PPD Virtual - Science 37, Inc
🇺🇸Culver City, California, United States
PRI, LLC - Los Alamitos - M3 WR
🇺🇸Los Alamitos, California, United States
PRI, LLC - Newport Beach - M3 WR
🇺🇸Newport Beach, California, United States
Reddy Care Medical
🇺🇸Pomona, California, United States
FOMAT Medical Research - FOMAT - HyperCore - PPDS
🇺🇸Oxnard, California, United States
Tekton Research - Fort Collins - PPDS
🇺🇸Fort Collins, Colorado, United States
Medical Center For Clinical Research - M3 WR
🇺🇸San Diego, California, United States
Paradigm Clinical Research Institute Inc - ClinEdge - PPDS
🇺🇸Wheat Ridge, Colorado, United States
Tekton Research - Longmont - PPDS
🇺🇸Longmont, Colorado, United States
Clinical Research Consultants LLC - ClinEdge - PPDS
🇺🇸Milford, Connecticut, United States
Washington Health Institute
🇺🇸Washington, District of Columbia, United States
Velocity Clinical Research, New Smyrna Beach
🇺🇸Edgewater, Florida, United States
Fleming Island Clinical Research Center
🇺🇸Fleming Island, Florida, United States
Velocity Clinical Research - Hallandale Beach - PPDS
🇺🇸Hallandale Beach, Florida, United States
Jacksonville Center for Clinical Research
🇺🇸Jacksonville, Florida, United States
Multi-Specialty Research Associates, Inc. M3 WR
🇺🇸Lake City, Florida, United States
Accel Research Sites - Maitland - ERN - PPDS
🇺🇸Maitland, Florida, United States
IMA Clinical Research - Manhattan - PPDS
🇺🇸Miami Beach, Florida, United States
Spotlight Research Center, LLC
🇺🇸Miami, Florida, United States
Health Awareness Inc
🇺🇸Port Saint Lucie, Florida, United States
IMA Clinical Research - Saint Petersburg - PPDS
🇺🇸Saint Petersburg, Florida, United States
AES - DRS - Synexus Clinical Research US, Inc. - St. Petersburg
🇺🇸Saint Petersburg, Florida, United States
Mount Vernon Clinical Research, LLC - M3 WR
🇺🇸Atlanta, Georgia, United States
Palm Beach Research - ClinEdge - PPDS
🇺🇸West Palm Beach, Florida, United States
Clinical Site Partners - Winter Park - HyperCore -PPDS
🇺🇸Winter Park, Florida, United States
Masters of Clinical Research Inc
🇺🇸Augusta, Georgia, United States
Centricity Research - Roswell - HyperCore - PPDS
🇺🇸Columbus, Georgia, United States
Javara, Inc./Privia Medical Group Georgia, LLC
🇺🇸Fayetteville, Georgia, United States
iResearch Atlanta
🇺🇸Decatur, Georgia, United States
Drug Studies America - ClinEdge - PPDS
🇺🇸Marietta, Georgia, United States
Velocity Clinical Research (Savannah - Georgia) - PPDS
🇺🇸Savannah, Georgia, United States
Randomize Now -Commerce Dr
🇺🇸Peachtree City, Georgia, United States
Clinical Research Atlanta - ERN-PPDS
🇺🇸Stockbridge, Georgia, United States
Velocity Clinical Research - Boise - PPDS
🇺🇸Meridian, Idaho, United States
DM Clinical - Chicago
🇺🇸River Forest, Illinois, United States
Velocity Clinical Research - Valparaiso - PPDS
🇺🇸Valparaiso, Indiana, United States
AES - DRS - Synexus Clinical Research US, Inc. - Chicago
🇺🇸Chicago, Illinois, United States
Affinity Health (Oak Brook)
🇺🇸Oak Brook, Illinois, United States
AES - DRS - Synexus Clinical Research US, Inc. - Evansville
🇺🇸Evansville, Indiana, United States
Johnson County Clin-Trials
🇺🇸Lenexa, Kansas, United States
Versailles Family Medicine - CCT - PPDS
🇺🇸Versailles, Kentucky, United States
Velocity Clinical Research (Baton Rouge - Louisiana) - PPDS
🇺🇸Baton Rouge, Louisiana, United States
Benchmark Research - Metairie - HyperCore - PPDS
🇺🇸Metairie, Louisiana, United States
Privia Medical Group, LLC - Annapolis - Javara - PPDS
🇺🇸Annapolis, Maryland, United States
CBH Health - CenExel CBH - PPDS
🇺🇸Gaithersburg, Maryland, United States
Great Lakes Research Institute
🇺🇸Southfield, Michigan, United States
Velocity Clinical Research (Rockville - Maryland) - PPDS
🇺🇸Rockville, Maryland, United States
AES - DRS - Synexus Clinical Research US, Inc. - St. Louis
🇺🇸Creve Coeur, Missouri, United States
AES - DRS - Synexus Clinical Research US, Inc. - Minneapolis
🇺🇸Richfield, Minnesota, United States
Montana Medical Research
🇺🇸Missoula, Montana, United States
Methodist Physicians Clinic - CCT Research - PPDS
🇺🇸Fremont, Nebraska, United States
Boeson Research MSO - Missoula - ERN - PPDS
🇺🇸Missoula, Montana, United States
Velocity Clinical Research (Grand Island - Nebraska) - PPDS
🇺🇸Grand Island, Nebraska, United States
Skyline Medical Center, PC - CCT Research
🇺🇸Elkhorn, Nebraska, United States
Velocity Clinical Research (Lincoln - Nebraska) - PPDS
🇺🇸Lincoln, Nebraska, United States
CCT Research
🇺🇸Papillion, Nebraska, United States
Excel Clinical Research - Las Vegas
🇺🇸Las Vegas, Nevada, United States
IMA Clinical Research - Raritan - PPDS
🇺🇸Raritan, New Jersey, United States
Velocity Clinical Research - East Syracuse - PPDS
🇺🇸East Syracuse, New York, United States
Riverside Medical Group - Circuit - PPDS
🇺🇸Secaucus, New Jersey, United States
AES - DRS - Synexus Clinical Research US, Inc. - New York
🇺🇸New York, New York, United States
Drug Trials America
🇺🇸Hartsdale, New York, United States
Velocity Clinical Research (Endwell - New York) - PPDS
🇺🇸Endwell, New York, United States
Rochester Clinical Research, Inc
🇺🇸Rochester, New York, United States
Carolina Institute for Clinical Research - M3 WR
🇺🇸Fayetteville, North Carolina, United States
Trial Management Associates, LLC
🇺🇸Wilmington, North Carolina, United States
Triad Clinical Trials
🇺🇸Greensboro, North Carolina, United States
CTI Clinical Research
🇺🇸Cincinnati, Ohio, United States
Velocity Clinical Research (Cincinnati - Ohio) - PPDS
🇺🇸Cincinnati, Ohio, United States
Tekton Research - Oklahoma - PPDS
🇺🇸Edmond, Oklahoma, United States
Hatboro Medical Associates - CCT - PPDS
🇺🇸Hatboro, Pennsylvania, United States
DM Clinical Research - Philadelphia - ERN - PPDS
🇺🇸Philadelphia, Pennsylvania, United States
Velocity Clinical Research (Dakota Dunes - South Dakota) - PPDS
🇺🇸Dakota Dunes, South Dakota, United States
American Indian Clinical Trials Research Network
🇺🇸Rapid City, South Dakota, United States
PanAmerican Clinical Research LLC
🇺🇸Brownsville, Texas, United States
Privia Medical Group- North Texas - West Parker Road - Fort Worth - Javara - PPDS
🇺🇸Fort Worth, Texas, United States
ACRC Trials - Carrollton - Hunt - PPDS
🇺🇸Carrollton, Texas, United States
Allure Health LLC
🇺🇸Friendswood, Texas, United States
Olympus Family Medicine- CCT
🇺🇸Friendswood, Texas, United States
Village Health Partners Frisco Medical Village
🇺🇸Frisco, Texas, United States
West Houston Clinical Research - Hunt - PPDS
🇺🇸Houston, Texas, United States
DM Clinical Research - Bellaire - ERN - PPDS
🇺🇸Houston, Texas, United States
DM Clinical-TCDD
🇺🇸Humble, Texas, United States
Helios CR, Inc. - Houston - PPDS
🇺🇸Keller, Texas, United States
AIM Trials
🇺🇸Plano, Texas, United States
Privia Medical Group- North Texas - Stephenville - Javara - PPDS
🇺🇸Stephenville, Texas, United States
DM Clinical Research - Sugarland - ERN - PPDS
🇺🇸Sugar Land, Texas, United States
Alpine Research Organization, Inc
🇺🇸Clinton, Utah, United States
DM Clinical Research - ERN
🇺🇸Tomball, Texas, United States
DM Clinical Research - ERN - PPDS
🇺🇸Tomball, Texas, United States
Cope Family Medicine - CCT - PPDS
🇺🇸Bountiful, Utah, United States
South Ogden Family Medicine - CCT
🇺🇸South Ogden, Utah, United States
Rainier Clinical Research Center
🇺🇸Renton, Washington, United States
Health Research of Hampton Roads Inc.
🇺🇸Newport News, Virginia, United States
Velocity Clinical Research - Family Practice - Portsmouth - PPDS
🇺🇸Portsmouth, Virginia, United States
Seattle Clinical Research Center
🇺🇸Seattle, Washington, United States
Instituto Medico Platense
🇦🇷Buenos Aires, Provincial De Buenos Aires, Argentina
Hospital Militar Central Cirujano Mayor Dr. Cosme Argerich
🇦🇷Ciudad Autónoma de BuenosAires, Argentina
Centro Medico Barrio Parque
🇦🇷Ciudad Autónoma de BuenosAires, Argentina
Fundación Dr. Mario Socolinsky - Centro de Vacunación Proteger
🇦🇷Ciudad Autónoma de BuenosAires, Argentina
Paratus Clinical Research - Canberra - PPDS
🇦🇺Bruce, Australian Capital Territory, Australia
Consultorios Médicos Dr. Doreski
🇦🇷Ciudad Autónoma de BuenosAires, Argentina
Paratus Clinical Research - Western Sydney - PPDS
🇦🇺Blacktown, New South Wales, Australia
Northern Beaches Clinical Research
🇦🇺Brookvale, New South Wales, Australia
Northside Health
🇦🇺Coffs Harbour, New South Wales, Australia
JHU-Projahnmo Zakiganj site
🇧🇩Zakiganj, Sylhet, Bangladesh
icddr,b Matlab Health Research Center
🇧🇩Chandpur, Bangladesh
Emeritus Research - PPDS
🇦🇺Camberwell, Victoria, Australia
Holdsworth House Medical Brisbane
🇦🇺Fortitude Valley, Queensland, Australia
Icddr,b Kamalapur Field Site
🇧🇩Dhaka, Bangladesh
JHU-Projahnmo Sylhet site
🇧🇩Sylhet, Bangladesh
ANIMA Research Center
🇧🇪Diepenbeek, Belgium
Vaccinopolis
🇧🇪Edegem, Belgium
Private Practice Dr Jean Benoit Martinot
🇧🇪Erpent, Belgium
CARe Clinic
🇨🇦Red Deer, Alberta, Canada
Okanagan Clinical Trials - Headlands - PPDS
🇨🇦Kelowna, British Columbia, Canada
Ziekenhuis Oost-Limburg
🇧🇪Genk, Belgium
Dr. Steven Z. Zizzo Medicine Professional Corporation
🇨🇦Hamilton, Ontario, Canada
Centricity Research - Toronto - HyperCore - PPDS
🇨🇦Etobicoke, Ontario, Canada
LMC Clinical Research Inc (Bayview)
🇨🇦Toronto, Ontario, Canada
Centricity Research - Quebec - HyperCore - PPDS
🇨🇦Levis, Quebec, Canada
Diex Recherche - Sherbrooke - PPDS
🇨🇦Sherbrooke, Quebec, Canada
Diex Recherche - Trois Rivieres - PPDS
🇨🇦Trois-Rivieres, Quebec, Canada
Diex Recherche - Joilette - PPDS
🇨🇦St-Charles-Borromee, Quebec, Canada
Hospital Base de Osorno
🇨🇱Osorno, Region De Los Lagos, Chile
Diex Recherche - Québec - PPDS
🇨🇦Québec, Canada
Centro Respiratorio Integral LTDA. (CENRESIN)
🇨🇱Quillota, Region De Valparaiso, Chile
Centro de Investigacion del Maule
🇨🇱Talca, Region Del Maule, Chile
Biomedica Research Group
🇨🇱Santiago, Region Metropolitana, Chile
BIOCINETIC SpA
🇨🇱Santiago, Region Metropolitana, Chile
Institucion Clinica de la Costa SAS
🇨🇴Barranquilla, Atlantico, Colombia
Centro de Atención e Investigación Médica S.A. - CAIMED - Aguazul
🇨🇴Aguazul, Casanare, Colombia
Solano & Terront Servicios Médicos LTDA (UNIENDO) Bogota
🇨🇴Bogota, Cundinamarca, Colombia
Centro de Atención e Investigación Médica S.A. - CAIMED - Chia
🇨🇴Chia, Cundinamarca, Colombia
Centro de Atención e Investigación Médica S.A. - CAIMED - Bogota
🇨🇴Bogota, Cundinamarca, Colombia
Centro de Atención e Investigación Médica S.A. - CAIMED - Girardot
🇨🇴Girardot, Cundinamarca, Colombia
IPS Centro de Investigacion Clinicas Cardiomet
🇨🇴Pereira, Risaralda, Colombia
Fundacion Oftalmologica de Santander Foscal
🇨🇴Floridablanca, Santandar, Colombia
Centro Medico Imbanaco de Cali S.A.
🇨🇴Cali, Valle De Cuaca, Colombia
Centro de Atención e Investigación Médica S.A. - CAIMED - Ibague
🇨🇴Ibague, Tolima, Colombia
Instituto de Investigación en Ciencias Médicas S.A.
🇨🇷San José, Costa Rica
Hospital CIMA San Jose
🇨🇷San José, Costa Rica
Campus Universidad EARTH, finca La Flor
🇨🇷Liberia, Guanacaste, Costa Rica
Hospital Clínica Bíblica Sede Santa Ana
🇨🇷San José, Costa Rica
Espoo Vaccine Research Clinic
🇫🇮Espoo, Finland
Helsinki South Vaccine Research Clinic
🇫🇮Helsinki, Finland
Helsinki East Vaccine Research Clinic
🇫🇮Helsinki, Finland
Järvenpää Vaccine Research Clinic
🇫🇮Järvenpää, Finland
KokkolaVaccine Research Clinic
🇫🇮Kokkola, Finland
Oulu Vaccine Research Clinic
🇫🇮Oulu, Finland
Seinäjoki Vaccine Research Clinic
🇫🇮Seinäjoki, Finland
Pori Vaccine Research Clinic
🇫🇮Pori, Finland
Turku Vaccine Research Clinic
🇫🇮Turku, Finland
Tampere Vaccine Research Clinic
🇫🇮Tampere, Finland
AES - DRS - Synexus Frankfurt Research Centre
🇩🇪Frankfurt, Hesse, Germany
Infektioresearch GmbH & Co. KG
🇩🇪Frankfurt, Hesse, Germany
Klinische Forschung, Schwerin GmbH (KFGN)
🇩🇪Schwerin, Mecklenburg-West Pomerania, Germany
Klinische Forschung Hannover-Mitte GmbH
🇩🇪Hannover, Lower Saxony, Germany
Medizentrum Essen Borbeck
🇩🇪Essen, North Rhine-Westphalia, Germany
AES - DRS - Synexus Berlin Research Centre
🇩🇪Berlin, Germany
Fukui General Clinic
🇯🇵Fukui-shi, Fukui, Japan
Tenjin Sogo Clinic
🇯🇵Fukuoka-shi, Fukuoka, Japan
Boocs Clinic Fukuoka
🇯🇵Hakata-ku, Fukuoka, Japan
Motomachi Takatsuka Naika Clinic
🇯🇵Naka-ku, Yokohama-ku, Kanagawa, Japan
Medical Corporation Asbo Tokyo Asbo Clinic
🇯🇵Chuo-ku, Tokyo, Japan
Center Hospital of the National Center for Global Health and Medicine
🇯🇵Shinjuku-ku, Tokyo, Japan
Higashi Shinjuku Clinic
🇯🇵Shinjuku-ku, Tokyo, Japan
NewHeart Watanabe Institute
🇯🇵Suginami-ku, Tokyo, Japan
SOUSEIKAI PS Clinic
🇯🇵Fukuoka, Japan
Sekino Hospital
🇯🇵Toshima-ku, Tokyo, Japan
Yonsei University Wonju Severance Christian Hospital
🇰🇷Wonju-si, Gangwon-do, Korea, Republic of
Inha University Hospital
🇰🇷Jung-gu, Incheon, Korea, Republic of
Samsung Medical Center - PPDS
🇰🇷Gangnam-gu, Seoul, Korea, Republic of
Ewha Womans University Seoul Hospital
🇰🇷Gangseo-gu, Seoul, Korea, Republic of
Dong-A University Hospital
🇰🇷Busan, Korea, Republic of
Chungnam National University Hospital
🇰🇷Daejeon, Korea, Republic of
Soon Chun Hyang University Hospital Bucheon
🇰🇷Gyeonggi-do, Korea, Republic of
Catholic Kwandong University International St. Mar
🇰🇷Incheon, Korea, Republic of
Severance Hospital Yonsei University Health System
🇰🇷Seoul, Korea, Republic of
Gangnam Severance Hospital, Yonsei University Health System
🇰🇷Seoul, Korea, Republic of
Accelerium, S. de R.L. de C.V.
🇲🇽Monterrey, Nuevo Leon, Mexico
Hallym University Kangnam Sacred Heart Hospital
🇰🇷Seoul, Korea, Republic of
Investigacion en Salud y Metabolismo S.C.
🇲🇽Chihuahua, Mexico
Maria del rayo morfin otero
🇲🇽Guadalajara, Jalisco, Mexico
AES - AS - RM Pharma Specialists Mexico City
🇲🇽Ciudad De Mexcio, Mexico
AES - AS - CEMDEC Mexico City
🇲🇽Ciudad De Mexcio, Mexico
Hospital General 450
🇲🇽Durango, Mexico
PanAmerican Clinical Research-Avenida
🇲🇽Querétaro, Mexico
Southern Clinical Trials Limited
🇳🇿Christchurch, Canterbury, New Zealand
Lakeland Clinical Trials
🇳🇿Rotorua, Canterbury, New Zealand
Southern Clinical Trials Waitemata
🇳🇿Auckland, New Zealand
New Zealand Clinical Research - Auckland
🇳🇿Auckland, New Zealand
Optimal Clinical Trials Ltd
🇳🇿Auckland, New Zealand
Southern Clinical Trials - Tasman
🇳🇿Nelson, New Zealand
CEVAXIN Avenida México
🇵🇦Panamá, Calidonia, Panama
CEVAXIN 24 de diciembre
🇵🇦Panamá, Panama
AES - DRS - Synexus Polska Sp. z o.o. Oddzial w Gdansku
🇵🇱Gdansk, Pomorskie, Poland
AES - DRS - Synexus Polska Sp. z o.o. Oddzial we Wroclawiu
🇵🇱Wroclaw, Dolnoslaskie, Poland
Ostrowieckie Centrum Medyczne Spólka Cywilna Anna Olech-Cudzik, Krzysztof Cudzik
🇵🇱Ostrowiec Swietokrzyski, Swietokrzyskie, Poland
AES - DRS - Synexus Polska Sp. z o.o. Oddzial w Katowicach
🇵🇱Katowice, Slaskie, Poland
Caribbean Medical Research Center
🇵🇷San Juan, Puerto Rico
AES - DRS - Synexus Polska Sp. z o.o. Oddzial w Poznaniu
🇵🇱Poznan, Wielkopolskie, Poland
Proyecto ACTU
🇵🇷San Juan, Puerto Rico
Dr. J Breedt
🇿🇦Pretoria, Gauteng, South Africa
Worthwhile Clinical Trials
🇿🇦Benoni, Gauteng, South Africa
AES - DRS - Synexus - Stanza Clinical Research Centre
🇿🇦Pretoria, Gauteng, South Africa
AES - DRS - Synexus Watermeyer Clinical Research Centre
🇿🇦Pretoria, Gauteng, South Africa
Aliwal Shoal Medical Center
🇿🇦Umkomaas, Kwazulu - Natal, South Africa
AES - DRS - Synexus - Helderberg Clinical Research Centre
🇿🇦Somerset West, Western Cape, South Africa
Hospital Son Llatzer
🇪🇸Son Ferriol, Palma De Mallorca, Spain
ABS Centelles
🇪🇸Centelles, Barcelona, Spain
Hospital Universitario de La Princesa
🇪🇸Madrid, Spain
China Medical University Hospital - PPDS
🇨🇳Taichung City, Taiwan
Taichung Veterans General Hospital
🇨🇳Taichung, Taiwan
Taipei Veterans General Hospital
🇨🇳Taipei City, Taiwan
Bristol Royal Infirmary
🇬🇧Bristol, Avon, United Kingdom
Chang Gung Memorial Hospital, Linkou
🇨🇳Taoyuan City, Taiwan
AES - DRS - NW Consortium Lancashire
🇬🇧Chorley, Lancashire, United Kingdom
AES - DRS - Synexus Scotland Clinical Research Centre
🇬🇧Bellshill, United Kingdom
AES - DRS - Synexus Hexham Clinical Research Centre
🇬🇧Hexham, Northumberland, United Kingdom
Royal Victoria Infirmary
🇬🇧Newcastle Upon Tyne, Tyne And Wear, United Kingdom
AES - DRS - Synexus Midlands Clinical Research Centre
🇬🇧Birmingham, United Kingdom
AES - DRS - Synexus Wales Clinical Research Centre
🇬🇧Cardiff, United Kingdom
AES - DRS - NW Consortium Merseyside
🇬🇧Liverpool, United Kingdom
AES - DRS - NW Consortium Manchester
🇬🇧Manchester, United Kingdom
AES - DRS - Synexus Polska Sp. z o.o. Oddzial w Warszawie
🇵🇱Warszawa, Mazowieckie, Poland
Benchmark Research - Covington - HyperCore - PPDS
🇺🇸Covington, Louisiana, United States
IMA Clinical Research - Monroe, LA - PPDS
🇺🇸Monroe, Louisiana, United States
Cheadle Hospital
🇬🇧Stoke-On-Trent, Staffordshire, United Kingdom
Singapore General Hospital (SGH)
🇸🇬Singapore, Singapore
BRCR Global Puerto Rico (Ponce)
🇵🇷Ponce, Puerto Rico
Hospital Universitario La Paz - PPDS
🇪🇸Madrid, Spain
AES - DRS - Synexus Clinical Research US, Inc. - Birmingham
🇺🇸Birmingham, Alabama, United States
Accel Research Site - Achieve - Birmingham
🇺🇸Birmingham, Alabama, United States
Hope Research Institute LLC - Phoenix - Hunt - PPDS
🇺🇸Phoenix, Arizona, United States
AES - DRS - Synexus Clinical Research US, Inc. - Phoenix Central
🇺🇸Phoenix, Arizona, United States
Synexus Clinical Research US, Inc. - Phoenix Southeast
🇺🇸Phoenix, Arizona, United States
Clinical Research Institute, Inc - CRN - PPDS
🇺🇸Minneapolis, Minnesota, United States
Affinity Health - Nashville
🇺🇸Nashville, Tennessee, United States
AES - DRS - Synexus Clinical Research US, Inc. - San Antonio
🇺🇸San Antonio, Texas, United States
Clinical Trials of Texas, LLC - HyperCore - PPDS
🇺🇸San Antonio, Texas, United States
Velocity Clinical Research (Omaha - Nebraska) - PPDS
🇺🇸Omaha, Nebraska, United States
Summit Research Network, Inc. - Portland - Headlands - PPDS
🇺🇸Portland, Oregon, United States
Layton Medical Centre
🇬🇧Blackpool, United Kingdom
FISABIO Oftalmología Médica (FOM)
🇪🇸Valencia, Spain
DM Clinical Research - Southfield - ERN - PPDS
🇺🇸Southfield, Michigan, United States
AES - DRS - Synexus Clinical Research US, Inc. - The Villages
🇺🇸Orlando, Florida, United States
Lynn Institute of Denver
🇺🇸Aurora, Colorado, United States
Clinical Trials of Tampa
🇺🇸Tampa, Florida, United States
East West Medical Research Institute
🇺🇸Honolulu, Hawaii, United States
DelRicht Clinical Research, LLC - Internal - Covington - PPDS
🇺🇸New Orleans, Louisiana, United States
Tekton Research
🇺🇸Austin, Texas, United States
Premier Family Physicians - Austin - Hunt - PPDS
🇺🇸Austin, Texas, United States