Clinical aspects and molecular mechanisms in large granular lymphocyte (LGL) leukemia - IDeAL study

Recruiting

• Conditions: blood cancer; Large granular lymphocyte leukemia; 10024324

• Registration Number: NL-OMON55452
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 150

Inclusion Criteria

Patients with LGL leukemia / lymphoproliferation

Exclusion Criteria

No consent

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Observational study without formal endpoints. At the end of this study, more<br /><br>insights will be gained about the following parameters:<br /><br>• fenotypical features<br /><br>• clonal TCR repertoire at DNA / RNA and possibly functional level<br /><br>• (epi)genetic and transcriptional patterns<br /><br>• (auto)antibodies and cytokines</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>NA</p>