Overnight Effects of nCPAP with and without humidification on upper airway function.

• Conditions: Obstructive Sleep Apnea; Respiratory - Sleep apnoea

• Registration Number: ACTRN12605000800628
• Lead Sponsor: Fisher and Paykel Healthcare

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2005-12-21
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

Moderate to severe obstructive sleep panea > 15 AHI > 75% of events must be obstructiveExcessive daytime sleepiness (ESS > 10).

Exclusion Criteria

Nasal CPAP intolerance determined in the PSG-CPAP titration studyacute upper airway diseasesmokerCOPDCongestive heart failure.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Saccharine transit time[Measured pre and post each overnight study]

Secondary Outcome Measures

Name	Time	Method
Mucus physical properties[Measured pre and post each overnight study.];Cytology via lavage[Measured pre and post each overnight study.];Inflammatory mediators[Measured pre and post each overnight study.];Upper airways symptom score[Measured pre and post each overnight study.]