An electronic nose in the screening for COPD in an at risk population of (ex-)smokers.
Completed
- Conditions
- COPD, smoking
- Registration Number
- NL-OMON20180
- Lead Sponsor
- Academic Medical CenterUniversity of AmsterdamDept. Pulmonology, F5-260Meibergdreef 91105 AZ AmsterdamThe NetherlandsUniversity Medical Center UtrechtUniversity of UtrechtDept. PulmonologyHeidelberglaan 1003584 CX UtrechtThe NetherlandsThe Nelson Study Group (Nederlands-Leuvens Longkanker Screeningsonderzoek).
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 250
Inclusion Criteria
1. > 40 years
2. Smoking or ex-smoking
Exclusion Criteria
1. Failure to complete eNose measurement
2. Not willing to participate in the study or lack of understanding
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Electronic nose smellprint of a vital capacity volume breath sample.<br>
- Secondary Outcome Measures
Name Time Method - Pre- and postbronchodilator spirometry according to ERS/ATS recommendations.<br /><br>- CO diffusion capacity according to ERS/ATS recommendations<br /><br>- Spiral CT scan of the thorax: presence and extent of emphesema<br /><br>- Questionnaires to assess symptoms of COPD, co-morbidity and smoking status.