The effect of perioperative Dexmedetomidine on renal function in patients undergoing CABG surgery and cardiopulmonary bypass
Phase 2
- Conditions
- Coronary Artery Bypass Grafting surgery and cardiopulmonary bypass.Atherosclerotic heart disease of native coronary arteryI25.1
- Registration Number
- IRCT20141009019470N83
- Lead Sponsor
- Shiraz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Age less than 70 years
Patients undergoing coronary artery bypass graft surgery
Exclusion Criteria
Emergency Surgery
Redo Surgery
Performing a coronary artery bypass graft surgery with other cardiac surgery
Preoperative renal problems and serum creatinine levels higher than 1.4
Ejection fraction less than 40%
Known liver problems or high levels of liver enzymes
Using balloon pump inside aorta.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum creatinine level. Timepoint: Before surgery, on the first, second and third days after surgery in ICU. Method of measurement: Blood sample.;Blood Urea Nitrogen. Timepoint: Before surgery, on the first, second and third days after surgery in ICU. Method of measurement: Blood sample.;Glomerular filtration rate. Timepoint: Before surgery, on the first, second and third days after surgery in ICU. Method of measurement: Cockcroft-Gault Equation Formula.
- Secondary Outcome Measures
Name Time Method Inotropic Consumption in ICU. Timepoint: Before surgery, on the first, second and third days after surgery in ICU. Method of measurement: Observation.