The effects of coffeine on reducing the fall of bloodpressure caused by postprandial hypotension in the elderly.

Completed

• Conditions: autonome functiestoornis nl. verminderde werking sympathische zenuwstelsel; bloodpressure reducement after a meal; postprandial hypotension

• Registration Number: NL-OMON37706
• Lead Sponsor: Medisch Centrum Leeuwarden

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 10

Inclusion Criteria

Admitted to the geriatrics in the Medical Centre Leeuwarden
Symptoms of hypotension after a meal
Normovolemia
Cardiac stability
Instructive
To be able to sit in a chair for two and a half hours
To be mentally competent

Exclusion Criteria

Dementia or not able to understand the study or not possible to be instructed.
To be mentally incompetent
If the first measurement without intervention shows no signs of postprandial hypotension.
Precency of pathology which results that coffee is not endured or the intake of cafeine is influenced.
No stable cardiac situation.
Dehydration.
If the patient is not used to drink any coffee and doesnot like it

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>30 minutes continuous measurement of systolic blood pressure in mmHg before<br /><br>the meal<br /><br>30 minutes continuous measurement of diastolic blood pressure in mmHg before<br /><br>the meal<br /><br>maximum systolic blood pressure reduction in mmHg<br /><br>maximum diastolic blood pressure reduction in mmHg<br /><br>duration in minutes when the maximum systolic and diastolic blood pressure<br /><br>reduction caused by PPH occurs .</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>average base value RR before the meal on all patients in mmHg<br /><br>maximum difference average systolic RR with average systolic base value on all<br /><br>patients in mmHg<br /><br>maximum difference average diastolic RR with average diastolic base value on<br /><br>all patients in mmHg<br /><br>average time in minutes after the start meal when maximum RR-differences due to<br /><br>PPH occur.<br /><br>Average duration in minutes when the maximum RR-increase due to coffeine occurs<br /><br><br /><br>average age of the patients<br /><br>determine how many men and how many women are included.</p><br>