Investigating the effect of caffeine in increasing the level of consciousness of patients with benzodiazepine poisoning
Phase 3
Recruiting
- Conditions
- Benzodiazepine poisoning.Poisoning by, adverse effect of and underdosing of benzodiazepinesT42.4
- Registration Number
- IRCT20091116002717N2
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Age above 14 years old
Benzodiazepine poisoning has been confirmed through the urine toxicology screen of the patient
Loss of consciousness
GCS less than 13
No head trauma
Do not have any contraindications to receiving flumazenil
No accompanying poisoning
Exclusion Criteria
Age below 14 years
Not having a positive urine screen for benzodiazepines
No loss of consciousness
GCS 14 15
Having head trauma
Having a contraindication to receiving flumazenil
Having accompanying poisoning
Allergy to caffeine
Having underlying metabolic disease
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method evel of consciousness. Timepoint: Every 8 hours. Method of measurement: GCS.
- Secondary Outcome Measures
Name Time Method The patient's time to wake up after receiving the first dose of caffeine. Timepoint: After administration of the first dose of caffeine and then every 24 hours. Method of measurement: hours and every 24 hours is considered a day.