Anti-Obesity Effect of Pediococcus Pentosaceus LP28
Not Applicable
Completed
- Conditions
- Obesity
- Interventions
- Dietary Supplement: PlaceboDietary Supplement: Live Pediococcus pentosaceus LP28Dietary Supplement: Heat-killed Pediococcus pentosaceus LP28
- Registration Number
- NCT01685944
- Lead Sponsor
- Hiroshima University
- Brief Summary
This study is designed to evaluate efficacy of Pediococcus pentosaceus LP28 in reducing body fat and body weight in subjects with BMI 25-30 kg/m2.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 62
Inclusion Criteria
- BMI 25-30 kg/m2
Exclusion Criteria
- Taking medicines or functional food that may affect body weight or body fat
- Pregnant or nursing a child
- Participation in any clinical trial within 90 days of the commencement of the trial
- Renal or hepatic dysfunction
- Heart disease
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Placebo Placebo - Live Pediococcus pentosaceus LP28 Live Pediococcus pentosaceus LP28 - Heat-killed Pediococcus pentosaceus LP28 Heat-killed Pediococcus pentosaceus LP28 -
- Primary Outcome Measures
Name Time Method BMI Every day (Overall 14 weeks) Body weight will be measured every morning.
Body fat Every 4 weeks (Overall 12 weeks)
- Secondary Outcome Measures
Name Time Method Fasting insulin Weeks 0 and 12 Adiponectin Weeks 0 and 12 Abdominal circumference Every 4 weeks (Overall 12 weeks) Serum triglyceride Every 4 weeks (Overall 12 weeks) Total cholesterol Every 4 weeks (Overall 12 weeks) Fasting blood glucose Every 4 weeks (Overall 12 weeks) HDL cholesterol Every 4 weeks (Overall 12 weeks) HOMA-R Weeks 0 and 12 LDL cholesterol Every 4 weeks (Overall 12 weeks) Resistin Weeks 0 and 12 Leptin Weeks 0 and 12
Trial Locations
- Locations (1)
Hiroshima University
🇯🇵Hiroshima, Japan