NL-OMON47825
Completed
Not Applicable
Bicuspid aortic valve stenosis and the effect of vItamin K2 on calciummetabolism on 18F-NaF PET/MRI (BASIK2): a pilot study - BASIK2
Medisch Universitair Ziekenhuis Maastricht0 sites44 target enrollmentTBD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Aortic valve calcification
- Sponsor
- Medisch Universitair Ziekenhuis Maastricht
- Enrollment
- 44
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Known with a bicuspid aortic valve and,
- •Calcified mild to moderate aortic valve stenosis on prior echocardiography
- •Age older than 18 years
- •Informed consent provided.
Exclusion Criteria
- •Absence of calcified aortic valve stenosis on echocardiography, presence of severe aortic valve stenosis, history of aortic valve repair or aortic valve replacement , scheduled for aortic valve replacement or repair , accepted atrial fibrillation, use of oral anticoagulants, claustrophobia, presence of a pacemaker or ICD or ferromagnetic materials in the body, adipositas permagna, history of (non treated) cancer within the previous two years (excep non\-melanoma skin cancer, carcinomas or in situ carcinoma of cervix), life expectancy of less than 2 years, wish for near future, or present pregnancy, breast feeding, (active) metabolic or gastrointestinal disease not controlled by current treatment, (history of) soy allergy, use of vitamin K\-containing supplements, chronic inflammatory disease, systemic treatment or topical treatment likely to interfere with evaluation of the study parameters, corticoid treatment, participation in a clinical study more recently than one month before the current study.
Outcomes
Primary Outcomes
Not specified
Similar Trials
Unknown
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