Pathogenic Mechanisms of Port Wine Stain and Repository of Port Wine Stain Biopsy Samples
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 19
- 试验地点
- 1
- 主要终点
- Characterization of Port Wine Stain Birthmark tissue sample
研究概览
简要总结
The purpose of this study is to investigate the pathogenic mechanisms of Port Wine Stain, collect biopsy samples and blood samples to characterize exosomes and metabolites from Port Wine Stain.
详细描述
The researcher can detect the defects in nervous system innervation to cutaneous blood vessels contribute to the pathogenesis of Port Wine Stain . Unveiling the pathogenic mechanisms of PWS is crucial to the design of new therapeutic strategies and can use the results to improve current PWS therapeutic outcomes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 1 Day 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Male or female of all ages.
- •Not pregnant.
- •Has diagnosis of port wine stain on the arms, legs, chest, bac.
- •Ability to understand and carry out subject instructions.
- •Subject willing to have skin biopsies on port wine stain and normal skin areas.
排除标准
- •Pregnant women.
- •Port Wine Stain on the face.
- •History of skin cancer.
- •Current participation in an investigational drug evaluation
- •Concurrent use of known photosensitizing drugs.
研究组 & 干预措施
Port Wine Stain Birthmark
Biopsy sample from Port Wine Stain Birthmark
干预措施: Biopsy sample from Port Wine Stain Birthmark (Other)
结局指标
主要结局
Characterization of Port Wine Stain Birthmark tissue sample
时间窗: up to 4 weeks
次要结局
未报告次要终点
研究者
Beckman Laser Institute and Medical Center
Wenbin Tan, Ph.D. Project Scientist
University of California, Irvine