Pathogenic Mechanisms of Port Wine Stain and Repository of Port Wine Stain Biopsy Samples
Not Applicable
Completed
- Conditions
- Port-Wine Stain
- Interventions
- Other: Biopsy sample from Port Wine Stain Birthmark
- Registration Number
- NCT02051101
- Lead Sponsor
- University of California, Irvine
- Brief Summary
The purpose of this study is to investigate the pathogenic mechanisms of Port Wine Stain, collect biopsy samples and blood samples to characterize exosomes and metabolites from Port Wine Stain.
- Detailed Description
The researcher can detect the defects in nervous system innervation to cutaneous blood vessels contribute to the pathogenesis of Port Wine Stain . Unveiling the pathogenic mechanisms of PWS is crucial to the design of new therapeutic strategies and can use the results to improve current PWS therapeutic outcomes.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 19
Inclusion Criteria
- Male or female of all ages.
- Not pregnant.
- Has diagnosis of port wine stain on the arms, legs, chest, bac.
- Ability to understand and carry out subject instructions.
- Subject willing to have skin biopsies on port wine stain and normal skin areas.
Exclusion Criteria
- Pregnant women.
- Port Wine Stain on the face.
- History of skin cancer.
- Current participation in an investigational drug evaluation
- Concurrent use of known photosensitizing drugs.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Port Wine Stain Birthmark Biopsy sample from Port Wine Stain Birthmark Biopsy sample from Port Wine Stain Birthmark
- Primary Outcome Measures
Name Time Method Characterization of Port Wine Stain Birthmark tissue sample up to 4 weeks
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Beckman Laser Institute
🇺🇸Irvine, California, United States