Maintenance Bee-Venom Immunotherapy Administered at 6-Month Intervals Does Not Protect Against re-Stings
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 60
- 主要终点
- whether the administration of bee venom (BV)
研究概览
简要总结
Maintenance venom immunotherapy administered at 6-month intervals to bee-venom allergic patients failed to provide protection from systemic reactions after sting challenges. These patients should continue their immunotherapy at 1-3 month intervals.
详细描述
Background: The intervals at which maintenance venom immunotherapy (MVIT) is administered have been progressively extended over the years.
Objective
To examine whether the administration of bee venom (BV) maintenance dose (MD) at 6-month interval is safe and efficacious.
Methods: The usual 3-month interval at which venom allergic patients were receiving their MVIT was gradually extended to 6 months. Systemic reactions (SRs) to immunotherapy injections or to field stings were regularly recorded. BV allergic patients were deliberately sting-challenged after reaching the 6-month interval.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 6 Years 至 75 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Venom allergy
排除标准
- 未提供
结局指标
主要结局
whether the administration of bee venom (BV)
maintenance dose (MD) at 6-month interval is safe and
efficacious.
次要结局
未报告次要终点