The effect of two different intraoperative inspired oxygen concentration on postoperative respiratory complications in patients above 60yrs of age undergoing elective surgery under general anesthesia: a randomized-controlled trial
Not Applicable
- Conditions
- Health Condition 1: PCS- Health Condition 2: K638- Other specified diseases of intestine
- Registration Number
- CTRI/2021/09/036699
- Lead Sponsor
- All India Institute of Medical Sciences AIIMS Jodhpur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients aged more than 60 years and scheduled for elective major surgery of duration more than 2 hours under general anaesthesia will be enrolled.
Exclusion Criteria
1.Patient undergoing cardio-thoracic surgery, thoracotomies
2.Patients with active upper or lower airway infection
3.Patients with abnormal preoperative chest Xâ??ray findings
4.Patients who are likely to require postoperative mechanical ventilation
5.Morbidly obese patients (BMI-35Kg/m2)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the incidence and severity of postoperative atelectasis determined by CT thorax.Timepoint: To compare the incidence and severity of postoperative atelectasis during postoperative period upto 24hrs determined by CT thorax.
- Secondary Outcome Measures
Name Time Method 1.To compare postoperative gas exchange by PaO2/FIO2.Timepoint: before preoxygenation and postoperatively at 1-hour, 6-hours and 12-hours;2.To compare incidence of postoperative nausea and vomiting.Timepoint: 24 hours postoperatively.;3.To compare incidence of surgical site infection.Timepoint: Till 5 days postoperatively.;4.To compare requirement of postoperative respiratory support (oxygen supplementation/ mechanical ventilation).Timepoint: Till day 3 postoperatively.;5.To compare incidence of postoperative pneumonia.Timepoint: Till day 3 postoperatively.