The Effect of Ultrasound-Guided Erector Spinae Plane Block on Postoperative Analgesia in Percutaneous Nephrolithotomy: a Randomised Single-blind Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 56
- 试验地点
- 1
- 主要终点
- Total 24-hour morphine consumption
研究概览
简要总结
This study is planned as a single-center randomized single blinded study and includes patients undergoing percutaneous nephrolitotomy.The aim of the study is to evaluate the effect of ultrasound guided erector spinal plane block on postoperative analgesia in percutaneous nephrolitotomy. Primary outcome is the total 24 hour morphine consumption.
详细描述
Adult patients aged 18-65 years with American Society of Anesthesiologists (ASA) physical status I-II scheduled for elective PCNL were allocated to receive either a unilateral ultrasound-guided ESPB at the T9 level with 20 mL of 0.25% bupivacaine followed by postoperative IV morphine PCA (Group ESPB ) or postoperative IV morphine PCA alone (Group C). 24 hour morphine consumption, numeric Rating Scale (NRS) pain scores, rescue analgesic requirements, sedation scores, opioid-related adverse effects, hospital stay, chronic pain, patient and surgeon satisfaction are recorded.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Elective percutaneous nephrolitotomy
- •American Society of Anesthesiologists (ASA) physical status I-II
排除标准
- •Refusal to participate
- •Coagulopathy,
- •Infection at the block site
- •Allergy to local anaesthetics
- •Previous surgery in the block area
- •Severe systemic disease.
研究组 & 干预措施
Group erector spinae plane block (Group ESPB)
Patients received erector spinae plane block for postoperative analgesia
干预措施: Erector Spinae Plane Block (Procedure)
Group Control (Group C)
Patients received only intravenous analgesia
干预措施: Intravenous analgesia (Procedure)
结局指标
主要结局
Total 24-hour morphine consumption
时间窗: 24 hours
Total 24-hour intravenous morphine consumption via patient controlled analgesia device
次要结局
- Pain assessment(24 hours)
- Additional analgesic requirement(24 hours)
- Postoperative nausea and vomiting(24 hours)
- Patient satisfaction(Up to 24 hours)
- Surgeon satisfaction(Up to 24 hours)
- First rescue analgesic time(24 hours)
- Length of hospital stay(Up to 1 week)
- Pruritus(24 hours)
- Chronic pain(3 months)
研究者
Meltem Savran Karadeniz
Attending Anesthesiologist
Istanbul University